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Clinical management of pruritus

The care of patients with chronic pruritus as a symptom of a wide variety of underlying diseases continues to confront dermatologists with diagnostic and therapeutic challenges. However, a structured history and a physical examination may already substantially help in narrowing down the number of po...

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Bibliographische Detailangaben
Hauptverfasser: Ständer, Sonja (VerfasserIn) , Weisshaar, Elke (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2015
In: Journal der Deutschen Dermatologischen Gesellschaft
Year: 2014, Jahrgang: 13, Heft: 2, Pages: 101-114
ISSN:1610-0387
DOI:10.1111/ddg.12522
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1111/ddg.12522
Verlag, Volltext: http://onlinelibrary.wiley.com/doi/10.1111/ddg.12522/abstract
Volltext
Verfasserangaben:Sonja Ständer, Claudia Zeidler, Nina Magnolo, Ulrike Raap, Thomas Mettang, Andreas E. Kremer, Elke Weisshaar, Matthias Augustin

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520 |a The care of patients with chronic pruritus as a symptom of a wide variety of underlying diseases continues to confront dermatologists with diagnostic and therapeutic challenges. However, a structured history and a physical examination may already substantially help in narrowing down the number of potential differential diagnoses. Apart form reducing the intensity of pruritus, identification and appropriate treatment of the underlying disease are important needs of patients. If these goals doesn't lead to improvement of itch, current guidelines provide a number of topical and systemic therapies for symptomatic treatment. Various skin lesions (for example, xerosis caused by irritant substances, secondary scratch lesions) prompt patients to consult a dermatologist, but most cases require an interdisciplinary therapeutic approach to identify potential internal medicine, neurologic, or psychosomatic aspects. Although great strides have been made in basic research, specific therapies are still rare, and a precise knowledge of the legal framework for the implementation of guidelines (for example, off-label use) is essential. This CME article gives an overview of the causes of and treatment options for chronic pruritus and discusses both advances in basic research as well as progress in clinical knowledge. 
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