Hox genes: realising the importance of realisators
A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in m...
Gespeichert in:
| 1. Verfasser: | |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
5 December 2006
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| In: |
Current biology
Year: 2006, Jahrgang: 16, Heft: 23, Pages: R988-R989 |
| ISSN: | 1879-0445 |
| DOI: | 10.1016/j.cub.2006.10.044 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1016/j.cub.2006.10.044 Verlag, kostenfrei, Volltext: http://www.sciencedirect.com/science/article/pii/S0960982206023827 |
| Verfasserangaben: | Ingrid Lohmann |
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| 520 | |a A recent study for the first time unravels a complete Hox regulatory network sufficient for the specification of a simple organ in Drosophila, linking Hox output to one specific group of executive genes, the realisators. As these genes have a direct effect on cellular functions and are required in most cell types, Hox genes may ultimately execute their function in controlling segmental fate by fine-tuning the spatial and temporal expression levels of these realisators. | ||
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