The evolution of cell types in animals: emerging principles from molecular studies

Cell types are fundamental units of multicellular life but their evolution is obscure. How did the first cell types emerge and become distinct in animal evolution? What were the sets of cell types that existed at important evolutionary nodes that represent eumetazoan or bilaterian ancestors? How did...

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1. Verfasser: Arendt, Detlev (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: November 2008
In: Nature reviews. Genetics
Year: 2008, Jahrgang: 9, Heft: 11, Pages: 868-882
ISSN:1471-0064
DOI:10.1038/nrg2416
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1038/nrg2416
Verlag, Volltext: http://www.nature.com/nrg/journal/v9/n11/full/nrg2416.html#top
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Verfasserangaben:Detlev Arendt
Beschreibung
Zusammenfassung:Cell types are fundamental units of multicellular life but their evolution is obscure. How did the first cell types emerge and become distinct in animal evolution? What were the sets of cell types that existed at important evolutionary nodes that represent eumetazoan or bilaterian ancestors? How did these ancient cell types diversify further during the evolution of organ systems in the descending evolutionary lines? The recent advent of cell type molecular fingerprinting has yielded initial insights into the evolutionary interrelationships of cell types between remote animal phyla and has allowed us to define some first principles of cell type diversification in animal evolution.
Beschreibung:Gesehen am 09.05.2017
Beschreibung:Online Resource
ISSN:1471-0064
DOI:10.1038/nrg2416