Complexity beneath the silence
Polycomb group (PcG)-mediated silencing by proteins that are conserved across plants and animals is a key feature of eukaryotic gene regulation. Investigation of PcG-mediated gene silencing has revealed a surprising degree of complexity in the molecular mechanisms that recruit the protein complexes,...
Gespeichert in:
| 1. Verfasser: | |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30 August 2006
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| In: |
Current opinion in plant biology
Year: 2006, Jahrgang: 9, Heft: 5, Pages: 530-537 |
| ISSN: | 1879-0356 |
| DOI: | 10.1016/j.pbi.2006.07.014 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.pbi.2006.07.014 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1369526606001208 
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| Verfasserangaben: | Myriam Calonje and Z. Renee Sung |
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| 520 | |a Polycomb group (PcG)-mediated silencing by proteins that are conserved across plants and animals is a key feature of eukaryotic gene regulation. Investigation of PcG-mediated gene silencing has revealed a surprising degree of complexity in the molecular mechanisms that recruit the protein complexes, repress expression, and maintain the epigenetic silent state of target genes. This review summarizes our current understanding of the mechanism of PcG-mediated gene silencing in animals and higher plants. | ||
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