Protein coevolution and isoexpression in yeast macromolecular complexes
Previous studies in the yeast Saccharomyces cerevisiae have shown that genes encoding subunits of macromolecular complexes have similar evolutionary rates (K) and expression levels (E). Besides, it is known that the expression of a gene is a strong predictor of its rate of evolution (i.e., E and K a...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 November 2006
|
| In: |
International journal of genomics
|
| ISSN: | 2314-4378 |
| DOI: | 10.1155/2007/58721 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1155/2007/58721 Verlag, kostenfrei, Volltext: https://www.hindawi.com/journals/ijg/2007/058721/abs/ 
|
| Verfasserangaben: | Laurence Ettwiller, Reiner A. Veitia |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1558534512 | ||
| 003 | DE-627 | ||
| 005 | 20220813171056.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 170511s2006 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1155/2007/58721 |2 doi | |
| 035 | |a (DE-627)1558534512 | ||
| 035 | |a (DE-576)488534518 | ||
| 035 | |a (DE-599)BSZ488534518 | ||
| 035 | |a (OCoLC)1340975264 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Ettwiller, Laurence |e VerfasserIn |0 (DE-588)1124859187 |0 (DE-627)879186666 |0 (DE-576)482506946 |4 aut | |
| 245 | 1 | 0 | |a Protein coevolution and isoexpression in yeast macromolecular complexes |c Laurence Ettwiller, Reiner A. Veitia |
| 264 | 1 | |c 23 November 2006 | |
| 300 | |a 4 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 11.05.2017 | ||
| 520 | |a Previous studies in the yeast Saccharomyces cerevisiae have shown that genes encoding subunits of macromolecular complexes have similar evolutionary rates (K) and expression levels (E). Besides, it is known that the expression of a gene is a strong predictor of its rate of evolution (i.e., E and K are correlated). Here we show that intracomplex variation of subunit expression correlates with intracomplex variation of their evolutionary rates (using two different measures of dispersion). However, a similar trend was observed for randomized complexes. Therefore, using a mathematical transformation, we created new variables capturing intracomplex variation of both E and K. The values of these new compound variables were smaller for real complexes than for randomized ones. This shows that proteins in complexes tend to have closer expressivities (E) and K's simultaneously than in the randomly grouped genes. We speculate about the possible implications of this finding. | ||
| 700 | 1 | |a Veitia, Reiner A. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of genomics |d [Hoboken, NJ] : Wiley, 2013 |g (2007) Article ID 58721, 4 Seiten |h Online-Ressource |w (DE-627)742225291 |w (DE-600)2711883-6 |w (DE-576)381276147 |x 2314-4378 |7 nnas |a Protein coevolution and isoexpression in yeast macromolecular complexes |
| 773 | 1 | 8 | |g year:2007 |g extent:4 |a Protein coevolution and isoexpression in yeast macromolecular complexes |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |a Ettwiller, Laurence |t Protein coevolution and isoexpression in yeast macromolecular complexes |d 2006 |w (DE-627)1558534199 |w (DE-576)488534194 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1155/2007/58721 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://www.hindawi.com/journals/ijg/2007/058721/abs/ |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20170511 | ||
| 993 | |a Article | ||
| 994 | |a 2006 | ||
| 998 | |g 1124859187 |a Ettwiller, Laurence |m 1124859187:Ettwiller, Laurence |p 1 |x j | ||
| 999 | |a KXP-PPN1558534512 |e 296928524X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1558534512","language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 11.05.2017"],"title":[{"title_sort":"Protein coevolution and isoexpression in yeast macromolecular complexes","title":"Protein coevolution and isoexpression in yeast macromolecular complexes"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Ettwiller, Laurence","given":"Laurence","family":"Ettwiller"},{"role":"aut","display":"Veitia, Reiner A.","roleDisplay":"VerfasserIn","given":"Reiner A.","family":"Veitia"}],"relHost":[{"part":{"year":"2007","extent":"4","text":"(2007) Article ID 58721, 4 Seiten"},"pubHistory":["2013 -"],"recId":"742225291","language":["eng"],"note":["Gesehen am 21.02.2025"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Protein coevolution and isoexpression in yeast macromolecular complexesInternational journal of genomics","title":[{"title":"International journal of genomics","title_sort":"International journal of genomics"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["2711883-6"],"eki":["742225291"],"doi":["10.1155/4140"],"issn":["2314-4378"]},"origin":[{"publisherPlace":"[Hoboken, NJ] ; New York, NY [u.a.]","dateIssuedKey":"2024","publisher":"Wiley ; Hindawi","dateIssuedDisp":"2024-"}]}],"physDesc":[{"extent":"4 S."}],"id":{"eki":["1558534512"],"doi":["10.1155/2007/58721"]},"origin":[{"dateIssuedDisp":"23 November 2006","dateIssuedKey":"2006"}],"name":{"displayForm":["Laurence Ettwiller, Reiner A. Veitia"]}} | ||
| SRT | |a ETTWILLERLPROTEINCOE2320 | ||