Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle by combinatorial use of bioinformatics tools
The pax2/5/8 genes belonging to the PAX family of transcription factors are key developmental regulators that are involved in the patterning of various embryonic tissues. More particularly, their function in inner ear specification has been widely described. However, little is known about the direct...
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| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 October 2008
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| In: |
Genome biology
Year: 2008, Volume: 9 |
| ISSN: | 1474-760X |
| DOI: | 10.1186/gb-2008-9-10-r145 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/gb-2008-9-10-r145
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| Author Notes: | Mirana Ramialison, Baubak Bajoghli, Narges Aghaallaei, Laurence Ettwiller, Sylvain Gaudan, Beate Wittbrodt, Thomas Czerny, Joachim Wittbrodt |
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| 520 | |a The pax2/5/8 genes belonging to the PAX family of transcription factors are key developmental regulators that are involved in the patterning of various embryonic tissues. More particularly, their function in inner ear specification has been widely described. However, little is known about the direct downstream targets and, so far, no global approaches have been performed to identify these target genes in this particular tissue. | ||
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