Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences
Changes in gene regulation are suspected to comprise one of the driving forces for evolution. To address the extent of cis-regulatory changes and how they impact on gene regulatory networks across eukaryotes, we systematically analyzed the evolutionary dynamics of target gene batteries controlled by...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 December 2008
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| In: |
Genome biology
Year: 2008, Jahrgang: 9 |
| ISSN: | 1474-760X |
| DOI: | 10.1186/gb-2008-9-12-r172 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/gb-2008-9-12-r172
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| Verfasserangaben: | Laurence Ettwiller, Aidan Budd, François Spitz, Joachim Wittbrodt |
| Zusammenfassung: | Changes in gene regulation are suspected to comprise one of the driving forces for evolution. To address the extent of cis-regulatory changes and how they impact on gene regulatory networks across eukaryotes, we systematically analyzed the evolutionary dynamics of target gene batteries controlled by 16 different transcription factors. |
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| Beschreibung: | Gesehen am 17.05.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 1474-760X |
| DOI: | 10.1186/gb-2008-9-12-r172 |