A systems biology study on NF[kappa]B signaling in primary mouse hepatocytes
The cytokine tumor necrosis factor-alpha (TNFα) is one of the key factors during the priming phase of liver regeneration as well as in hepatocarcinogenesis. TNFα activates the nuclear factor κ-light-chain-enhancer of activated B cells (NFκB) signalling pathway and contributes to the conversion of qu...
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| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
31. December 2012
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| In: |
Frontiers in physiology
Year: 2012, Volume: 3 |
| ISSN: | 1664-042X |
| DOI: | 10.3389/fphys.2012.00466 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.3389/fphys.2012.00466 Verlag, Volltext: http://journal.frontiersin.org/article/10.3389/fphys.2012.00466/full |
| Author Notes: | Federico Pinna, Sven Sahle, Katharina Beuke, Michaela Bissinger, Selcan Tuncay, Lorenza D'Alessandro, Ralph Gauges, Andreas Raue, Jens Timmer, Ursula Klingmüller, Peter Schirmacher, Ursula Kummer and Kai Breuhahn |
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TNF-induced NF-[kappa]B signal transduction in the liver
2016
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