A systems biology study on NF[kappa]B signaling in primary mouse hepatocytes

The cytokine tumor necrosis factor-alpha (TNFα) is one of the key factors during the priming phase of liver regeneration as well as in hepatocarcinogenesis. TNFα activates the nuclear factor κ-light-chain-enhancer of activated B cells (NFκB) signalling pathway and contributes to the conversion of qu...

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Main Authors: Pinna, Federico (Author) , Sahle, Sven (Author) , Beuke, Katharina (Author) , Bissinger, Michaela (Author) , Aydin, Selcan (Author) , D'Alessandro, Lorenza (Author) , Gauges, Ralph (Author) , Raue, Andreas (Author) , Timmer, Jens (Author) , Klingmüller, Ursula (Author) , Schirmacher, Peter (Author) , Kummer, Ursula (Author) , Breuhahn, Kai (Author)
Format: Article (Journal)
Language:English
Published: 31. December 2012
In: Frontiers in physiology
Year: 2012, Volume: 3
ISSN:1664-042X
DOI:10.3389/fphys.2012.00466
Online Access:Verlag, Volltext: http://dx.doi.org/10.3389/fphys.2012.00466
Verlag, Volltext: http://journal.frontiersin.org/article/10.3389/fphys.2012.00466/full
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Author Notes:Federico Pinna, Sven Sahle, Katharina Beuke, Michaela Bissinger, Selcan Tuncay, Lorenza D'Alessandro, Ralph Gauges, Andreas Raue, Jens Timmer, Ursula Klingmüller, Peter Schirmacher, Ursula Kummer and Kai Breuhahn
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Model-based identification of TNFα-induced IKKβ-mediated and I[kappa]Bα-mediated regulation of NF[kappa]B signal transduction as a tool to quantify the impact of drug-induced liver... by Oppelt, Angela (Author) , Kaschek, Daniel (Author) , Huppelschoten, Suzanna (Author) , Sison-Young, Rowena (Author) , Zhang, Fang (Author) , Buck-Wiese, Marie (Author) , Herrmann, Franziska (Author) , Malkusch, Sebastian (Author) , Krüger, Carmen L. (Author) , Meub, Mara (Author) , Merkt, Benjamin (Author) , Zimmermann, Lea (Author) , Schofield, Amy (Author) , Jones, Robert P. (Author) , Malik, Hassan (Author) , Schilling, Marcel (Author) , Heilemann, Mike (Author) , Water, Bob van de (Author) , Goldring, Christopher E. (Author) , Park, B. Kevin (Author) , Timmer, Jens (Author) , Klingmüller, Ursula (Author) ,


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A20/TNFAIP3 discriminates tumor necrosis factor (TNF)-induced NF-[kappa]B from JNK pathway activation in hepatocytes by Pinna, Federico (Author) , Bissinger, Michaela (Author) , Beuke, Katharina (Author) , Huber, Nicolas Peter (Author) , Kummer, Ursula (Author) , Schirmacher, Peter (Author) , Sahle, Sven (Author) , Breuhahn, Kai (Author) ,


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TNF-induced NF-[kappa]B signal transduction in the liver by Beuke, Katharina (Author)

2016

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