The latent Dementia phenotype [delta] is associated with cerebrospinal fluid biomarkers of Alzheimer’s disease and predicts conversion to dementia in subjects with mild cognitive impairment

Background: The recently proposed latent variable δ is a new tool for dementia case finding. It is built in a structural equation modeling framework of cognitive and functional data and constitutes a novel endophenotype for Alzheimer’s disease (AD)

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Bibliographic Details
Main Authors: Koppara, Alexander (Author) , Frölich, Lutz (Author) , Schröder, Johannes (Author)
Format: Article (Journal)
Language:English
Published: 2016
In: Journal of Alzheimer's disease
Year: 2016, Volume: 49, Issue: 2, Pages: 547-560
ISSN:1875-8908
DOI:10.3233/JAD-150257
Online Access:Verlag, Volltext: http://dx.doi.org/10.3233/JAD-150257
Verlag, Volltext: http://content.iospress.com/articles/journal-of-alzheimers-disease/jad150257
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Author Notes:Alexander Koppara, Steffen Wolfsgruber, Luca Kleineidam, Klaus Schmidtke, Lutz Frölich, Alexander Kurz, Stefanie Schulz, Harald Hampel, Isabella Heuser, Oliver Peters, Friedel M. Reischies, Holger Jahn, Christian Luckhaus, Michael Hüll, Hermann-Josef Gertz, Johannes Schröder, Johannes Pantel, Otto Rienhoff, Eckart Rüther, Fritz Henn, Jens Wiltfang, Wolfgang Maier, Frank Jessen, Johannes Kornhuber, Michael Wagner

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