The latent Dementia phenotype [delta] is associated with cerebrospinal fluid biomarkers of Alzheimer’s disease and predicts conversion to dementia in subjects with mild cognitive impairment
Background: The recently proposed latent variable δ is a new tool for dementia case finding. It is built in a structural equation modeling framework of cognitive and functional data and constitutes a novel endophenotype for Alzheimer’s disease (AD)
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| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
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| In: |
Journal of Alzheimer's disease
Year: 2016, Volume: 49, Issue: 2, Pages: 547-560 |
| ISSN: | 1875-8908 |
| DOI: | 10.3233/JAD-150257 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.3233/JAD-150257 Verlag, Volltext: http://content.iospress.com/articles/journal-of-alzheimers-disease/jad150257 |
| Author Notes: | Alexander Koppara, Steffen Wolfsgruber, Luca Kleineidam, Klaus Schmidtke, Lutz Frölich, Alexander Kurz, Stefanie Schulz, Harald Hampel, Isabella Heuser, Oliver Peters, Friedel M. Reischies, Holger Jahn, Christian Luckhaus, Michael Hüll, Hermann-Josef Gertz, Johannes Schröder, Johannes Pantel, Otto Rienhoff, Eckart Rüther, Fritz Henn, Jens Wiltfang, Wolfgang Maier, Frank Jessen, Johannes Kornhuber, Michael Wagner |
MARC
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