Cover Image

Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil)

Acute cytotoxicity (neutral red assay), AhR-mediated toxicity (CYP P450 1A induction potential—EROD assay) and concentrations of PAHs were recorded in RTL-W1 cells to assess the ecotoxicological potential of sediments from reservoirs along the Tietê River and the Pinheiros River (Brazil). Almost al...

Full description

Saved in:
Bibliographic Details
Main Authors: Rocha, Paula Suares (Author) , Storch, Volker (Author) , Braunbeck, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 13 January 2010
In: Ecotoxicology and environmental safety
Year: 2010, Volume: 73, Issue: 4, Pages: 550-558
ISSN:1090-2414
DOI:10.1016/j.ecoenv.2009.12.017
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.ecoenv.2009.12.017
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0147651309002942
Get full text
Author Notes:Paula Suares Rocha, Ehab Azab, Burkhard Schmidt, Volker Storch, Henner Hollert, Thomas Braunbeck

MARC

LEADER 00000caa a2200000 c 4500
001 1559691751
003 DE-627
005 20220813182401.0
007 cr uuu---uuuuu
008 170613s2010 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.ecoenv.2009.12.017  |2 doi 
035 |a (DE-627)1559691751 
035 |a (DE-576)489691757 
035 |a (DE-599)BSZ489691757 
035 |a (OCoLC)1340976108 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 32  |2 sdnb 
100 1 |a Rocha, Paula Suares  |d 1976-  |e VerfasserIn  |0 (DE-588)140220291  |0 (DE-627)703603973  |0 (DE-576)315107294  |4 aut 
245 1 0 |a Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil)  |c Paula Suares Rocha, Ehab Azab, Burkhard Schmidt, Volker Storch, Henner Hollert, Thomas Braunbeck 
264 1 |c 13 January 2010 
300 |a 9 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 13.06.2017 
520 |a Acute cytotoxicity (neutral red assay), AhR-mediated toxicity (CYP P450 1A induction potential—EROD assay) and concentrations of PAHs were recorded in RTL-W1 cells to assess the ecotoxicological potential of sediments from reservoirs along the Tietê River and the Pinheiros River (Brazil). Almost all sediments tested induced cytotoxicity and stimulated cytochrome P450-associated EROD activity. Toxicity increases from Tietê River spring to São Paulo city region and decreases towards downstream. A closer analysis of chemical measurements of PAHs and results from bioassay revealed that the PAHs analyzed could not explain more than 7% of the EROD-inducing potencies. Results confirm that most of the toxicity is due to the discharges of the metropolitan area of São Paulo. Moreover, they indicate additional sources of pollutants along the river course, which contribute to the degradation of each reservoir. 
650 4 |a Acute cytotoxicity 
650 4 |a Brazil 
650 4 |a CYP P450 1A 
650 4 |a EROD assay 
650 4 |a Neutral red assay 
650 4 |a PAHs 
650 4 |a Pinheiros River 
650 4 |a RTL-W1 cell line 
650 4 |a Sediments 
650 4 |a Tietê River 
700 1 |a Storch, Volker  |d 1943-  |e VerfasserIn  |0 (DE-588)106365495  |0 (DE-627)476591961  |0 (DE-576)163213445  |4 aut 
700 1 |a Braunbeck, Thomas  |e VerfasserIn  |0 (DE-588)106835819X  |0 (DE-627)82017839X  |0 (DE-576)165906731  |4 aut 
773 0 8 |i Enthalten in  |t Ecotoxicology and environmental safety  |d Amsterdam : Elsevier, 1977  |g 73(2010), 4, Seite 550-558  |h Online-Ressource  |w (DE-627)266018467  |w (DE-600)1466969-9  |w (DE-576)104193719  |x 1090-2414  |7 nnas  |a Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil) 
773 1 8 |g volume:73  |g year:2010  |g number:4  |g pages:550-558  |g extent:9  |a Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil) 
856 4 0 |u http://dx.doi.org/10.1016/j.ecoenv.2009.12.017  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u http://www.sciencedirect.com/science/article/pii/S0147651309002942  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20170613 
993 |a Article 
994 |a 2010 
998 |g 106835819X  |a Braunbeck, Thomas  |m 106835819X:Braunbeck, Thomas  |d 700000  |d 721000  |e 700000PB106835819X  |e 721000PB106835819X  |k 0/700000/  |k 1/700000/721000/  |p 6  |y j 
998 |g 106365495  |a Storch, Volker  |m 106365495:Storch, Volker  |d 700000  |d 721000  |e 700000PS106365495  |e 721000PS106365495  |k 0/700000/  |k 1/700000/721000/  |p 4 
998 |g 140220291  |a Rocha, Paula Suares  |m 140220291:Rocha, Paula Suares  |d 700000  |d 721000  |e 700000PR140220291  |e 721000PR140220291  |k 0/700000/  |k 1/700000/721000/  |p 1  |x j 
999 |a KXP-PPN1559691751  |e 2971826473 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Paula Suares Rocha, Ehab Azab, Burkhard Schmidt, Volker Storch, Henner Hollert, Thomas Braunbeck"]},"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1559691751","id":{"eki":["1559691751"],"doi":["10.1016/j.ecoenv.2009.12.017"]},"origin":[{"dateIssuedDisp":"13 January 2010","dateIssuedKey":"2010"}],"note":["Gesehen am 13.06.2017"],"physDesc":[{"extent":"9 S."}],"person":[{"family":"Rocha","given":"Paula Suares","display":"Rocha, Paula Suares","role":"aut"},{"role":"aut","display":"Storch, Volker","given":"Volker","family":"Storch"},{"family":"Braunbeck","given":"Thomas","display":"Braunbeck, Thomas","role":"aut"}],"title":[{"title":"Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil)","title_sort":"Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil)"}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedKey":"1977","publisherPlace":"Amsterdam ; Orlando, Fla.","dateIssuedDisp":"1977-","publisher":"Elsevier ; Academic Press"}],"note":["Gesehen am 14.01.2021"],"pubHistory":["1.1977/78; 2.1978 - 38.1997; 58.2004 - 74.2011; Vol. 75.2012 -"],"id":{"zdb":["1466969-9"],"issn":["1090-2414"],"eki":["266018467"]},"recId":"266018467","part":{"text":"73(2010), 4, Seite 550-558","pages":"550-558","issue":"4","year":"2010","volume":"73","extent":"9"},"corporate":[{"role":"isb","display":"International Society for Ecotoxicology and Environmental Safety"}],"title":[{"title_sort":"Ecotoxicology and environmental safety","title":"Ecotoxicology and environmental safety","subtitle":"EES ; official journal of the International Society of Ecotoxicology and Environmental safety"}],"disp":"Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil)Ecotoxicology and environmental safety","titleAlt":[{"title":"EES"},{"title":"Environmental research / B"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"]}]} 
SRT |a ROCHAPAULACHANGESINT1320 

Similar Items