Transient global amnesia in legal proceedings
Transient global amnesia (TGA) is a neurological disorder characterized by an acute onset of severe anterograde amnesia. While retrograde amnesia may be present - although to a lesser extent - patients have no further cognitive disturbances or neurological signs. These symptoms resolve fully within...
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2015
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| In: |
International journal of legal medicine
Year: 2015, Jahrgang: 129, Heft: 1, Pages: 223-226 |
| ISSN: | 1437-1596 |
| DOI: | 10.1007/s00414-014-1038-5 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00414-014-1038-5 Verlag, Volltext: https://link-springer-com.ezproxy.medma.uni-heidelberg.de/article/10.1007/s00414-014-1038-5 |
| Verfasserangaben: | Martin Griebe, Hansjörg Bäzner, Micha Kablau, Michael G. Hennerici, Kristina Szabo |
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| 520 | |a Transient global amnesia (TGA) is a neurological disorder characterized by an acute onset of severe anterograde amnesia. While retrograde amnesia may be present - although to a lesser extent - patients have no further cognitive disturbances or neurological signs. These symptoms resolve fully within several hours leaving a permanent memory gap for the duration of the episode and do not lead to long-term neurological deficits. In addition to well-defined clinical diagnostic criteria, in up to 80 % of patients, small, point-shaped lesions in the hippocampus are detected 24-48 h after symptom onset on diffusion-weighted magnetic resonance images. Despite several etiological hypotheses, to date, there is no scientific proof for the etiology of TGA or the small hippocampal lesions. Interestingly, in a large number of cases, an emotionally or physically straining event precipitates the onset of TGA, suggesting a stress-related mechanism. We report two cases of TGA occurring in legally relevant settings: affecting the victim of brutal burglary and the key witness in a murder trial. In the context of forensic medicine, the knowledge of this disorder and recognition of its typical features are essential. | ||
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