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Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice

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Leukemia immunotherapy frequently does not meet expectation, one of the handicaps being tumor exosome (TEX)-promoted immunosuppression. We here asked, using the mouse myeloid leukemia WEHI3B and the renal cell carcinoma line RENCA, whether dendritic cell (DC) vaccination suffices to counterregulate...

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Main Authors: Gu, Xiaoyu (Author) , Erb, Ulrike (Author) , Büchler, Markus W. (Author) , Zöller, Margot (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: International journal of cancer
Year: 2014, Volume: 136, Issue: 4, Pages: E74-E84
ISSN:1097-0215
DOI:10.1002/ijc.29100
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/ijc.29100
Verlag, kostenfrei, Volltext: http://onlinelibrary.wiley.com/doi/10.1002/ijc.29100/abstract
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Author Notes:Xiaoyu Gu, Ulrike Erb, Markus W. Büchler and Margot Zöller
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Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice by Gu, Xiaoyu (Author)

2015

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