Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer

In a randomized trial comparing pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and docetaxel, the pertuzumab combination resulted in a median overall survival of 56 months in women with metastatic HER2-positive breast cancer.

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Bibliographic Details
Main Authors: Swain, Sandra M. (Author) , Schneeweiss, Andreas (Author)
Format: Article (Journal)
Language:English
Published: February 19, 2015
In: The New England journal of medicine
Year: 2015, Volume: 372, Issue: 8, Pages: 724-734
ISSN:1533-4406
DOI:10.1056/NEJMoa1413513
Online Access:Verlag, Volltext: http://dx.doi.org/10.1056/NEJMoa1413513
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Author Notes:Sandra M. Swain, M.D., José Baselga, M.D., Sung-Bae Kim, M.D., Jungsil Ro, M.D., Vladimir Semiglazov, M.D., Mario Campone, M.D., Eva Ciruelos, M.D., Jean-Marc Ferrero, M.D., Andreas Schneeweiss, M.D., Sarah Heeson, B.Sc., Emma Clark, M.Sc., Graham Ross, F.F.P.M., Mark C. Benyunes, M.D., and Javier Cortés, M.D., for the CLEOPATRA Study Group

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