Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization

Compartmentalization is a key feature of eukaryotic cells, but its evolution remains poorly understood. GTPases are the oldest enzymes that use nucleotides as substrates and they participate in a wide range of cellular processes. Therefore, they are ideal tools for comparative genomic studies aimed...

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Bibliographic Details
Main Authors: Reynaud, Emmanuel G. (Author) , Andrade, Miguel Almeida (Author) , Knop, Michael (Author) , Scheffzek, Klaus (Author) , Pepperkok, Rainer (Author)
Format: Article (Journal)
Language:English
Published: 07 October 2005
In: BMC biology
Year: 2005, Volume: 3
ISSN:1741-7007
DOI:10.1186/1741-7007-3-21
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1741-7007-3-21
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Author Notes:Emmanuel G. Reynaud, Miguel A. Andrade, Fabien Bonneau, Thi Bach Nga Ly, Michael Knop, Klaus Scheffzek and Rainer Pepperkok
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Summary:Compartmentalization is a key feature of eukaryotic cells, but its evolution remains poorly understood. GTPases are the oldest enzymes that use nucleotides as substrates and they participate in a wide range of cellular processes. Therefore, they are ideal tools for comparative genomic studies aimed at understanding how aspects of biological complexity such as cellular compartmentalization evolved.
Item Description:Gesehen am 21.08.2017
Physical Description:Online Resource
ISSN:1741-7007
DOI:10.1186/1741-7007-3-21