Patient position and hypoxemia during propofol sedation for colonoscopy: a randomized trial
Aim: To evaluate the benefits of the left lateral position in avoiding hypoxemic events in patients undergoing colonoscopy. Methods: We conducted a randomized, prospective, controlled trial at two study sites in Germany. Patients undergoing colonoscopy under propofol sedation were randomized to eith...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30.6.2015
|
| In: |
Endoscopy
Year: 2015, Jahrgang: 47, Heft: 12, Pages: 1159-1166 |
| ISSN: | 1438-8812 |
| DOI: | 10.1055/s-0034-1392329 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0034-1392329 Verlag, Volltext: http://www.thieme-connect.de.ezproxy.medma.uni-heidelberg.de/DOI/DOI?10.1055/s-0034-1392329 
|
| Verfasserangaben: | Peter Klare, Raffaela Huth, Bernhard Haller, Martin Huth, Andreas Weber, Christoph Schlag, Wolfgang Reindl, Roland M. Schmid, Stefan von Delius |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1563679000 | ||
| 003 | DE-627 | ||
| 005 | 20220813225106.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 170920s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1055/s-0034-1392329 |2 doi | |
| 035 | |a (DE-627)1563679000 | ||
| 035 | |a (DE-576)493679006 | ||
| 035 | |a (DE-599)BSZ493679006 | ||
| 035 | |a (OCoLC)1340979478 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Klare, Peter |d 1980- |e VerfasserIn |0 (DE-588)135759714 |0 (DE-627)571246117 |0 (DE-576)283275278 |4 aut | |
| 245 | 1 | 0 | |a Patient position and hypoxemia during propofol sedation for colonoscopy |b a randomized trial |c Peter Klare, Raffaela Huth, Bernhard Haller, Martin Huth, Andreas Weber, Christoph Schlag, Wolfgang Reindl, Roland M. Schmid, Stefan von Delius |
| 264 | 1 | |c 30.6.2015 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 20.09.2017 | ||
| 520 | |a Aim: To evaluate the benefits of the left lateral position in avoiding hypoxemic events in patients undergoing colonoscopy. Methods: We conducted a randomized, prospective, controlled trial at two study sites in Germany. Patients undergoing colonoscopy under propofol sedation were randomized to either the supine or left lateral position. The primary outcome was oxygen desaturation (SaO<sub>2</sub> < 90 %). Secondary outcome measures were apneic events, hypotension, patient satisfaction, propofol dosage, cecal intubation time, and adenoma detection. Results: A total of 412 patients were randomized 1:1 to undergo colonoscopy in the supine or left lateral position. No severe adverse events were observed in either group. Intention-to-treat analysis revealed no significant difference in the frequency of desaturation in the left lateral arm compared with the supine arm (6.8 % vs. 12.1 %; P = 0.064). Patients in the left lateral arm showed lower apnea rates (9.4 % vs. 16.2 %; P = 0.040), but had more episodes of hypotension (12.3 % vs. 2.9 %; P < 0.001). The frequency of repositioning was higher in the left lateral group. No significant differences were observed in patient satisfaction and cooperation, propofol dosage, or adenoma detection rate. Patients who were repositioned to facilitate endoscope passage were excluded from per-protocol analysis. The incidence of hypoxemia was lower for the left lateral than for the supine group in per-protocol analysis (1.8 % vs. 11.2 %; P = 0.003). Conclusion: The positioning of patients in the left lateral position during propofol sedation for colonoscopy results in lower desaturation rates provided the position can be maintained throughout endoscopy. ClinicalTrials.gov NCT02001792. | ||
| 700 | 1 | |a Reindl, Wolfgang |d 1971- |e VerfasserIn |0 (DE-588)1071925237 |0 (DE-627)826644430 |0 (DE-576)433441054 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Endoscopy |d Stuttgart [u.a.] : Thieme, 1969 |g 47(2015), 12, Seite 1159-1166 |h Online-Ressource |w (DE-627)323606229 |w (DE-600)2026213-9 |w (DE-576)255101643 |x 1438-8812 |7 nnas |a Patient position and hypoxemia during propofol sedation for colonoscopy a randomized trial |
| 773 | 1 | 8 | |g volume:47 |g year:2015 |g number:12 |g pages:1159-1166 |g extent:8 |a Patient position and hypoxemia during propofol sedation for colonoscopy a randomized trial |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1055/s-0034-1392329 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.thieme-connect.de.ezproxy.medma.uni-heidelberg.de/DOI/DOI?10.1055/s-0034-1392329 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20170920 | ||
| 993 | |a Article | ||
| 994 | |a 2015 | ||
| 998 | |g 1071925237 |a Reindl, Wolfgang |m 1071925237:Reindl, Wolfgang |d 60000 |e 60000PR1071925237 |k 0/60000/ |p 7 | ||
| 999 | |a KXP-PPN1563679000 |e 2981111000 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"8 S."}],"name":{"displayForm":["Peter Klare, Raffaela Huth, Bernhard Haller, Martin Huth, Andreas Weber, Christoph Schlag, Wolfgang Reindl, Roland M. Schmid, Stefan von Delius"]},"recId":"1563679000","id":{"eki":["1563679000"],"doi":["10.1055/s-0034-1392329"]},"relHost":[{"id":{"eki":["323606229"],"issn":["1438-8812"],"zdb":["2026213-9"],"doi":["10.1055/s-00000012"]},"pubHistory":["1.1969 -"],"recId":"323606229","physDesc":[{"extent":"Online-Ressource"}],"language":["ger"],"note":["Gesehen am 06.11.2013"],"origin":[{"publisherPlace":"Stuttgart [u.a.]","dateIssuedDisp":"1969-","publisher":"Thieme","dateIssuedKey":"1969"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"title":[{"title_sort":"Endoscopy","subtitle":"official organ of the European Society of Gastrointestinal Endoscopy (E.S.G.E.) and affiliated societies","title":"Endoscopy"}],"part":{"issue":"12","year":"2015","text":"47(2015), 12, Seite 1159-1166","pages":"1159-1166","extent":"8","volume":"47"},"corporate":[{"role":"isb","display":"European Society of Gastrointestinal Endoscopy"}],"disp":"Patient position and hypoxemia during propofol sedation for colonoscopy a randomized trialEndoscopy"}],"person":[{"display":"Klare, Peter","family":"Klare","role":"aut","given":"Peter"},{"display":"Reindl, Wolfgang","family":"Reindl","role":"aut","given":"Wolfgang"}],"title":[{"title":"Patient position and hypoxemia during propofol sedation for colonoscopy","subtitle":"a randomized trial","title_sort":"Patient position and hypoxemia during propofol sedation for colonoscopy"}],"note":["Gesehen am 20.09.2017"],"origin":[{"dateIssuedKey":"2015","dateIssuedDisp":"30.6.2015"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"]} | ||
| SRT | |a KLAREPETERPATIENTPOS3062 | ||