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Intracardiac yolk sac tumor in an infant girl

We report about a two and a half year old girl with a primary yolk sac tumor (YST) of the heart, located in the interventricular septum. The girl was admitted to the hospital with a systolic cardiac murmur. Echocardiography revealed a smoothly surfaced tumor which based on the interventricular septu...

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Bibliographische Detailangaben
Hauptverfasser: Graf, Matthias (VerfasserIn) , Bläker, Hendrik (VerfasserIn) , Schnabel, Philipp Albert (VerfasserIn) , Serpi, Mario (VerfasserIn) , Ulmer, Herbert E. (VerfasserIn) , Otto, Herwart F. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1999
In: Pathology, research and practice
Year: 1999, Jahrgang: 195, Heft: 3, Pages: 193-197
ISSN:1618-0631
DOI:10.1016/S0344-0338(99)80034-X
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/S0344-0338(99)80034-X
Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pubmed/10220801
Volltext
Verfasserangaben:Matthias Graf, Hendrik Blaeker, Philipp Schnabel, Mario Serpi, Herbert E. Ulmer and Herwart F. Otto

MARC

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520 |a We report about a two and a half year old girl with a primary yolk sac tumor (YST) of the heart, located in the interventricular septum. The girl was admitted to the hospital with a systolic cardiac murmur. Echocardiography revealed a smoothly surfaced tumor which based on the interventricular septum below the aortic valve and filled out more than half of the left ventricular cavity. Diagnosis of a yolk sac tumor was established on a frozen section of a biopsy taken at surgery and confirmed by the examination of the resected material. Excessively elevated serum alpha-fetoprotein (AFP) levels contributed to this diagnosis. Follow up examinations of the patient including computed tomography (CT) of head, thorax and abdomen, did not indicate an extracardiac tumor manifestation. We found no previous report of a primary intracardial yolk sac tumor in the literature. 
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