Nab-paclitaxel/gemcitabine first line therapy in patients with metastatic pancreatic carcinoma and high-bilirubin values: data from the German QoliXane pancreatic cancer registry

© The Author 2016. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissionsoup.com.Background: Hyperbilirubinaemia is a common disease effect in patients (pts) with metastatic pancreatic canc...

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Hauptverfasser: Hausen, Gerrit zur (VerfasserIn) , Springfeld, Christoph (VerfasserIn) , Härtel, Nicolai (VerfasserIn) , Hofheinz, Ralf-Dieter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 11 October 2016
In: Annals of oncology
Year: 2016, Jahrgang: 27
ISSN:1569-8041
DOI:10.1093/annonc/mdw371.76
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1093/annonc/mdw371.76
Verlag, kostenfrei, Volltext: https://academic.oup.com/annonc/article/27/suppl_6/684P/2799431
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Verfasserangaben:G. zur Hausen, O. Waidmann, M.A. Woerns, H.G. Hoeffkes, S. Doerfel, M.O. Zahn, A. Aldaoud, M. Stauch, C. Springfeld, N. Haertel, A. Reichart, T.O. Goetze, S. Schwarz, C. Pauligk, J. Roemmler-Zehrer, R.D. Hofheinz, S.-E. Al-Batran

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520 |a © The Author 2016. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissionsoup.com.Background: Hyperbilirubinaemia is a common disease effect in patients (pts) with metastatic pancreatic cancer (mPC). As clinical trials often exclude them, data on management of these pts are rare. In the framework of a German observational multicenter study (QoliXane), quality of life and therapy data are currently being collected in pts with mPC receiving a combination of nab-paclitaxel and gemcitabine. This is an interim analysis on hyperbilirubinaemia management.Methods: Pts were included to this analysis if they entered the trial with a bilirubin level ≥ 1.2 mg/dl and completed at least 2 cycles. Bilirubin levels were documented for up to 4 cycles and methods of hyperbilirubinaemia management have been assessed. A both descriptive and explorative analysis was performed using IBM SPSS V 23.Results:... 
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