Applicability and discriminative value of a semiautomatic three-dimensional spherical volume for the assessment of the apparent diffusion coefficient in suspicious breast lesions: feasibility study
To evaluate the feasibility and accuracy of a semiautomatic, three-dimensional volume of interest (3D sphere) for measuring the apparent diffusion coefficient (ADC) in suspicious breast lesions compared to conventional single-slice two-dimensional regions of interest (2D ROIs). This institutional-re...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30 August 2016
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| In: |
Clinical imaging
Year: 2016, Jahrgang: 40, Heft: 6, Pages: 1280-1285 |
| ISSN: | 1873-4499 |
| DOI: | 10.1016/j.clinimag.2016.08.022 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.clinimag.2016.08.022 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0899707116301176 
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| Verfasserangaben: | Jan Hering, Frederik Bernd Laun, Wolfgang Lederer, Heidi Daniel, Tristan Anselm Kuder, Anne Stieber, Stefan Delorme, Klaus H. Maier-Hein, Heinz-Peter Schlemmer, Sebastian Bickelhaupt |
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| 245 | 1 | 0 | |a Applicability and discriminative value of a semiautomatic three-dimensional spherical volume for the assessment of the apparent diffusion coefficient in suspicious breast lesions |b feasibility study |c Jan Hering, Frederik Bernd Laun, Wolfgang Lederer, Heidi Daniel, Tristan Anselm Kuder, Anne Stieber, Stefan Delorme, Klaus H. Maier-Hein, Heinz-Peter Schlemmer, Sebastian Bickelhaupt |
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| 520 | |a To evaluate the feasibility and accuracy of a semiautomatic, three-dimensional volume of interest (3D sphere) for measuring the apparent diffusion coefficient (ADC) in suspicious breast lesions compared to conventional single-slice two-dimensional regions of interest (2D ROIs). This institutional-review-board-approved study included 56 participants with Breast Imaging Reporting and Data System 4/5 lesion. All received diffusion-weighted imaging magnetic resonance imaging prior to biopsy (b=0-1500 s/mm2). ADC values were measured in the lesions with both methods. Reproducibility and accuracies were compared. Area under the curve was 0.93 [95% confidence interval (CI) 0.86-0.99] for the 3D sphere and 0.91 (95% CI 0.84-0.98) for the 2D ROIs without significantly differing reproducibility (P=.45). A semiautomatic 3D sphere could reliably estimate ADC values in suspicious breast lesions without significant difference compared to conventional 2D ROIs. | ||
| 650 | 4 | |a Automatic lesion analysis | |
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Breast MRI | |
| 650 | 4 | |a Diffusion-weighted imaging (DWI) | |
| 650 | 4 | |a Spherical metrics | |
| 700 | 1 | |a Stieber, Anne |e VerfasserIn |0 (DE-588)111704873X |0 (DE-627)870924613 |0 (DE-576)478697228 |4 aut | |
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