Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14

Background. Contact: allergy to rubber additives is common, particularly in patients with occupational dermatitis. Objectives: to descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional ‘rubber series’ as used in the depart...

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Hauptverfasser: Uter, Wolfgang (VerfasserIn) , Weisshaar, Elke (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 5 June 2016
In: Contact dermatitis
Year: 2016, Jahrgang: 75, Heft: 6, Pages: 345-352
ISSN:1600-0536
DOI:10.1111/cod.12651
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1111/cod.12651
Verlag, Volltext: http://onlinelibrary.wiley.com/doi/10.1111/cod.12651/abstract
Volltext
Verfasserangaben:Wolfgang Uter, Katharine Warburton, Elke Weisshaar, Dagmar Simon, Barbara Ballmer-Weber, Vera Mahler, Thomas Fuchs, Johannes Geier and Mark Wilkinson

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520 |a Background. Contact: allergy to rubber additives is common, particularly in patients with occupational dermatitis. Objectives: to descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional ‘rubber series’ as used in the department. Methods: patch test data from those members of the European Surveillance System on Contact Allergies (ESSCA) network (www.essca-dc.org) who also contributed data on rubber series patch test results were retrospectively analysed. Results: among 29 522 patients patch tested, 2870 were eligible, that is, patch tested both with the baseline series and with a special rubber series. Of these, 8.8% had positive reaction(s) to one of the baseline screening rubber allergens (as compared with 4.2% in all patients), most often to carba mix, 12.3% had positive reaction(s) to allergens from an additional rubber series, and 6.4% had positive reaction(s) to both. Conclusions: additional testing with a dedicated rubber series, containing break-down single ingredients of mixes from the baseline series and additional rubber allergens, is warranted in patients with suspected contact allergy to rubber, to avoid false-negative results. 
650 4 |a clinical epidemiology 
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