Hepatitis delta virus: insights into a peculiar pathogen and novel treatment options
Co-infection with HBV and HDV is considered to be the most severe form of viral hepatitis, affecting 15-20 million individuals worldwide HDV is an RNA virusoid that depends on HBV envelope proteins for its assembly, and host cellular proteins to facilitate its replication Current treatment options f...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
18 August 2016
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| In: |
Nature reviews. Gastroenterology & hepatology
Year: 2016, Jahrgang: 13, Heft: 10, Pages: 580-589 |
| ISSN: | 1759-5053 |
| DOI: | 10.1038/nrgastro.2016.126 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1038/nrgastro.2016.126 Verlag, Volltext: https://www.nature.com/articles/nrgastro.2016.126 
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| Verfasserangaben: | Florian A. Lempp, Yi Ni, Stephan Urban |
| Zusammenfassung: | Co-infection with HBV and HDV is considered to be the most severe form of viral hepatitis, affecting 15-20 million individuals worldwide HDV is an RNA virusoid that depends on HBV envelope proteins for its assembly, and host cellular proteins to facilitate its replication Current treatment options for chronic HDV infection are limited to interferon regimes Three novel antivirals targeting virus entry or particle assembly and/or secretion have shown promising results in phase II clinical trials |
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| Beschreibung: | Gesehen am 04.12.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 1759-5053 |
| DOI: | 10.1038/nrgastro.2016.126 |