The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Patricia Munroe, Christopher Newton-Cheh, Andrew Morris and colleagues perform association studies in over 340,000 individuals of European ancestry and identify 66 loci, of which 17 are novel, involved in blood pressure regulation. The risk SNPs are enriched for <i>cis</i>-regulatory ele...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 September 2016
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| In: |
Nature genetics
Year: 2016, Jahrgang: 48, Heft: 10, Pages: 1171-1184 |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/ng.3667 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1038/ng.3667 Verlag, Volltext: https://www.nature.com/articles/ng.3667 
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| Verfasserangaben: | Georg B. Ehret, Marcus E. Kleber [und 314 andere] |
| Zusammenfassung: | Patricia Munroe, Christopher Newton-Cheh, Andrew Morris and colleagues perform association studies in over 340,000 individuals of European ancestry and identify 66 loci, of which 17 are novel, involved in blood pressure regulation. The risk SNPs are enriched for <i>cis</i>-regulatory elements, particularly in vascular endothelial cells. |
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| Beschreibung: | Gesehen am 06.12.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/ng.3667 |