Bistability of cell-matrix adhesions resulting from nonlinear receptor-ligand dynamics
Bistability is a major mechanism for cellular decision making and usually results from positive feedback in biochemical control systems. Here we show theoretically that bistability between unbound and bound states of adhesion clusters results from positive feedback mediated by structural rather than...
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| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
6 January 2009
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| In: |
Biophysical journal
Year: 2006, Volume: 91, Issue: 6, Pages: L60-L62 |
| ISSN: | 1542-0086 |
| DOI: | 10.1529/biophysj.106.090209 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1529/biophysj.106.090209 Verlag, kostenfrei, Volltext: http://www.sciencedirect.com/science/article/pii/S0006349506719129 
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| Author Notes: | Thorsten Erdmann and Ulrich S. Schwarz |
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Bistability of cell-matrix adhesions resulting from non-linear receptor-ligand dynamics
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