L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events
L-selectin mediated tethers result in leukocyte rolling only above a threshold in shear. Here we present biophysical modeling based on recently published data from flow chamber experiments (Dwir et al., J. Cell Biol. 163: 649-659, 2003) which supports the interpretation that L-selectin mediated teth...
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| Main Authors: | , |
|---|---|
| Format: | Article (Journal) Chapter/Article |
| Language: | English |
| Published: |
2005
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| In: |
Arxiv
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| Online Access: | Verlag, kostenfrei, Volltext: http://arxiv.org/abs/q-bio/0504008
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| Author Notes: | Ulrich S. Schwarz, Theory Division, Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany; Ronen Alon, Department of Immunology, Weizmann Institute of Science, Rehovot, 76100 Israel |
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