Force-spectrum relations for molecular optical force probes
Force probes allow real-time monitoring of forces acting in different regions of large molecules and are potentially suited for the investigation of structural changes occurring in macromolecules during, e. g., folding processes.1-10 Such information is crucial for the understanding of mechanochemic...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
31 January 2014
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| In: |
Angewandte Chemie. International edition
Year: 2014, Volume: 53, Issue: 10, Pages: 2759-2761 |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201309794 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1002/anie.201309794 Verlag, Volltext: http://onlinelibrary.wiley.com/doi/10.1002/anie.201309794/abstract 
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| Author Notes: | Tim Stauch and Andreas Dreuw |
| Summary: | Force probes allow real-time monitoring of forces acting in different regions of large molecules and are potentially suited for the investigation of structural changes occurring in macromolecules during, e. g., folding processes.1-10 Such information is crucial for the understanding of mechanochemical reactivity.2, 3, 6, 7 To this end, small molecular force probes can be incorporated into large molecules.2, 3, 11-13 Some of the available systems are based on mechanochromism, the change of the UV/Vis absorption spectrum of a molecule under mechanical stress.1, 14 Herein we propose the idea of using molecular force probes in which the point-group symmetry is reduced as a result of mechanical deformation. This effect leads to significant and characteristic changes in the UV/Vis, IR, and Raman spectra of the deformed molecules, which were determined using computational methods. Beneficially, these changes are reversible and occur even if the applied forces are small. |
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| Item Description: | Gesehen am 15.12.2017 |
| Physical Description: | Online Resource |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201309794 |