Antidepressant treatment with venlafaxine and mirtazapine: no effect on serum concentration of Vascular Endothelial Growth Factor (VEGF)
Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline...
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| 1. Verfasser: | |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
2015
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| In: |
Pharmacopsychiatry
Year: 2015, Jahrgang: 48, Heft: 07, Pages: 292-293 |
| ISSN: | 1439-0795 |
| DOI: | 10.1055/s-0035-1555849 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0035-1555849 Verlag, Volltext: http://www.thieme-connect.de.ezproxy.medma.uni-heidelberg.de/DOI/DOI?10.1055/s-0035-1555849 |
| Verfasserangaben: | M. Deuschle, M. Gilles, B. Scharnholz, K.G. Kahl |
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| 520 | |a Introduction: Depression, stress and antidepressant treatment have been found to modulate the expression of growth factors. Methods: We studied depressed patients receiving randomized treatment with venlafaxine or mirtazapine for 28 days. Results: There was no significant difference between baseline VEGF concentrations in depressed patients compared to healthy controls. We found no significant effect of antidepressant treatment on serum VEGF. Discussion: In contrast to serum BDNF, VEGF may not be a suitable biomarker for effects of antidepressant treatment with venlafaxine or mirtazapine. | ||
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