Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56dim natural killer cells
The role of natural killer (NK) cells in granulomatosis with polyangiitis (GPA) is poorly understood. We recently reported that peripheral blood NK cell percentages correlate with the suppression of GPA activity (cohort I). The purpose of the current study was to further characterize NK cell subsets...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
13 September 2016
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| In: |
Arthritis Research & Therapy
Year: 2016, Jahrgang: 18 |
| ISSN: | 1465-9913 |
| DOI: | 10.1186/s13075-016-1098-7 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13075-016-1098-7 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13075-016-1098-7 
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| Verfasserangaben: | Wolfgang Merkt, Maren Claus, Norbert Blank, Michael Hundemer, Adelheid Cerwenka, Hanns-Martin Lorenz and Carsten Watzl |
| Zusammenfassung: | The role of natural killer (NK) cells in granulomatosis with polyangiitis (GPA) is poorly understood. We recently reported that peripheral blood NK cell percentages correlate with the suppression of GPA activity (cohort I). The purpose of the current study was to further characterize NK cell subsets, phenotype and function in a second GPA cohort (cohort II). |
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| Beschreibung: | Gesehen am 22.12.2017 |
| Beschreibung: | Online Resource |
| ISSN: | 1465-9913 |
| DOI: | 10.1186/s13075-016-1098-7 |