Subcutaneous implantable cardioverter-defibrillator: first single-center experience with other cardiac implantable electronic devices

The subcutaneous implantable cardioverter-defibrillator (S-ICD) is an implantable device for antiarrhythmic therapy with no intravascular leads. The purpose of this study was to describe the technical feasibility of combining the S-ICD with other cardiac implantable electronic devices (CIEDs), inclu...

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Main Authors: Kuschyk, Jürgen (Author) , Stach-Jablonski, Ksenija (Author) , Tueluemen, Erol (Author) , Rudic, Boris (Author) , Liebe, Volker (Author) , Schimpf, Rainer (Author) , Borggrefe, Martin (Author) , Röger, Susanne (Author)
Format: Article (Journal)
Language:English
Published: November 2015
In: Heart rhythm
Year: 2015, Volume: 12, Issue: 11, Pages: 2230-2238
ISSN:1556-3871
DOI:10.1016/j.hrthm.2015.06.022
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.hrthm.2015.06.022
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1547527115007134
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Author Notes:Jürgen Kuschyk, Ksenija Stach, Erol Tülümen, Boris Rudic, Volker Liebe, Rainer Schimpf, Martin Borggrefe, Susanne Röger

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520 |a The subcutaneous implantable cardioverter-defibrillator (S-ICD) is an implantable device for antiarrhythmic therapy with no intravascular leads. The purpose of this study was to describe the technical feasibility of combining the S-ICD with other cardiac implantable electronic devices (CIEDs), including pacemakers with transvenous or epicardial electrodes. We also provide the first experience of combining an S-ICD with catheter-based therapies, including cardiac contractility modulation (CCM) and vagus nerve stimulation. Between July 2011 and November 2014, 6 patients received a CCM device and S-ICD, 3 patients with a single-chamber pacemaker using either transvenous or epicardial pacing electrodes received and S-ICD, and 1 patient with an implanted S-ICD received vagus nerve stimulation. In all patients, intraoperative S-ICD testing, crosstalk tests, and postoperative ergometric testing were performed. In all 10 patients, device implantations were successfully performed without complications. S-ICD therapy was shown to be technically feasible with concomitant CIED. Mean follow-up was nearly 17 months. S-ICD testing and crosstalk testing before and during exercise enabled device programming across a broad range of test conditions and was associated with no subsequent evidence of adverse device interaction. None of the devices required permanent inactivation or removal, and no patient received an inappropriate shock. In suitable patients, combining an S-ICD with CCM or pacemaker may provide an acceptable means to reduce the number of transvascular leads. S-ICD appeared safe with CCM over an intermediate follow-up period. Additional prospective randomized controlled trials examining S-ICD in conjunction with CIEDs are warranted. 
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