Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells

Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative medicine, tissue engineering and immunotherapy. This is based on their differentiation potential and the supply of pro-regenerative and immunomodulatory signals. MSC can be isolated from a multitude of tissue sources, but...

Full description

Saved in:
Bibliographic Details
Main Authors: Mattar, Philipp (Author) , Bieback, Karen (Author)
Format: Article (Journal)
Language:English
Published: 03 November 2015
In: Frontiers in immunology
Year: 2015, Volume: 6, Pages: 1-8
ISSN:1664-3224
DOI:10.3389/fimmu.2015.00560
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.3389/fimmu.2015.00560
Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2015.00560/full
Get full text
Author Notes:Philipp Mattar, Karen Bieback

MARC

LEADER 00000caa a2200000 c 4500
001 1566836611
003 DE-627
005 20240807123932.0
007 cr uuu---uuuuu
008 180103s2015 xx |||||o 00| ||eng c
024 7 |a 10.3389/fimmu.2015.00560  |2 doi 
035 |a (DE-627)1566836611 
035 |a (DE-576)496836617 
035 |a (DE-599)BSZ496836617 
035 |a (OCoLC)1340985650 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Mattar, Philipp  |d 1991-  |e VerfasserIn  |0 (DE-588)1149781726  |0 (DE-627)1010091395  |0 (DE-576)496836730  |4 aut 
245 1 0 |a Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells  |c Philipp Mattar, Karen Bieback 
264 1 |c 03 November 2015 
300 |a 8 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 03.01.2018 
520 |a Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative medicine, tissue engineering and immunotherapy. This is based on their differentiation potential and the supply of pro-regenerative and immunomodulatory signals. MSC can be isolated from a multitude of tissue sources, but mainly bone marrow, adipose tissue and birth-associated tissues (e.g. umbilical cord, cord blood, placenta) appear to be relevant for clinical translation in immune-mediated disorders. However, only a few studies directly compared the immunomodulatory potency of MSC from different tissue sources. This review compiles the current literature regarding the similarities and differences between these three sources for MSCs with a special focus on their immunomodulatory effects on T-lymphocyte subsets and monocytes, macrophages and dendritic cells. 
650 4 |a Adipose Tissue 
650 4 |a Bone Marrow 
650 4 |a Immunomodulation 
650 4 |a Macrophages 
650 4 |a Mesenchymal Stromal Cells 
650 4 |a regulatory T cells 
650 4 |a T cells 
650 4 |a Umbilical Cord 
700 1 |a Bieback, Karen  |d 1972-  |e VerfasserIn  |0 (DE-588)124509991  |0 (DE-627)376254653  |0 (DE-576)294206604  |4 aut 
773 0 8 |i Enthalten in  |t Frontiers in immunology  |d Lausanne : Frontiers Media, 2010  |g 6(2015), Artikel-ID 560, Seite 1-8  |h Online-Ressource  |w (DE-627)657998354  |w (DE-600)2606827-8  |w (DE-576)343624834  |x 1664-3224  |7 nnas  |a Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells 
773 1 8 |g volume:6  |g year:2015  |g elocationid:560  |g pages:1-8  |g extent:8  |a Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells 
856 4 0 |u http://dx.doi.org/10.3389/fimmu.2015.00560  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
856 4 0 |u https://www.frontiersin.org/articles/10.3389/fimmu.2015.00560/full  |x Verlag  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20180103 
993 |a Article 
994 |a 2015 
998 |g 124509991  |a Bieback, Karen  |m 124509991:Bieback, Karen  |d 60000  |d 63500  |e 60000PB124509991  |e 63500PB124509991  |k 0/60000/  |k 1/60000/63500/  |p 2  |y j 
998 |g 1149781726  |a Mattar, Philipp  |m 1149781726:Mattar, Philipp  |d 60000  |e 60000PM1149781726  |k 0/60000/  |p 1  |x j 
999 |a KXP-PPN1566836611  |e 2991613076 
BIB |a Y 
SER |a journal 
JSO |a {"id":{"doi":["10.3389/fimmu.2015.00560"],"eki":["1566836611"]},"recId":"1566836611","physDesc":[{"extent":"8 S."}],"note":["Gesehen am 03.01.2018"],"name":{"displayForm":["Philipp Mattar, Karen Bieback"]},"person":[{"role":"aut","display":"Mattar, Philipp","roleDisplay":"VerfasserIn","given":"Philipp","family":"Mattar"},{"role":"aut","display":"Bieback, Karen","roleDisplay":"VerfasserIn","given":"Karen","family":"Bieback"}],"title":[{"title":"Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells","title_sort":"Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells"}],"origin":[{"dateIssuedKey":"2015","dateIssuedDisp":"03 November 2015"}],"relHost":[{"note":["Gesehen am 07.11.13"],"pubHistory":["1.2010 -"],"physDesc":[{"extent":"Online-Ressource"}],"recId":"657998354","id":{"zdb":["2606827-8"],"issn":["1664-3224"],"eki":["657998354"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"part":{"year":"2015","text":"6(2015), Artikel-ID 560, Seite 1-8","pages":"1-8","extent":"8","volume":"6"},"disp":"Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cellsFrontiers in immunology","origin":[{"publisher":"Frontiers Media","dateIssuedKey":"2010","publisherPlace":"Lausanne","dateIssuedDisp":"2010-"}],"title":[{"title_sort":"Frontiers in immunology","title":"Frontiers in immunology"}]}],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"}} 
SRT |a MATTARPHILCOMPARINGT0320