Aktuelle Aspekte zur Ototoxizität: ototoxische Substanzen und deren Effekte = Current aspects of ototoxicity
Ototoxicity describes reversible or irreversible disorders of inner ear functions due to the influence of chemical, biological, or physical substances. Ototoxicity should be kept in mind during differential diagnosis of hearing loss, tinnitus, dizziness, and vertigo. In clinical practice, drug-induc...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | German |
| Published: |
25. Januar 2015
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| In: |
HNO
Year: 2015, Volume: 63, Issue: 4, Pages: 315-326 |
| ISSN: | 1433-0458 |
| DOI: | 10.1007/s00106-014-2966-6 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1007/s00106-014-2966-6 Verlag, Volltext: https://link.springer.com/article/10.1007/s00106-014-2966-6 
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| Author Notes: | L.E. Walther, R. Hülse, K. Lauer, A. Wenzel |
| Summary: | Ototoxicity describes reversible or irreversible disorders of inner ear functions due to the influence of chemical, biological, or physical substances. Ototoxicity should be kept in mind during differential diagnosis of hearing loss, tinnitus, dizziness, and vertigo. In clinical practice, drug-induced ototoxic effects play a major role. The otorhinolaryngologist should also be involved in interdisciplinary cooperation, e.g., during treatment with antineoplastic chemotherapeutic agents with potential ototoxic side effects. In clinical practice, multimedication and interactions between different agents can complicate precise correlation in individual cases. Recent studies also show that noncellular components, such as otoconia, are extremely sensitive to chemical attacks. |
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| Item Description: | Gesehen am 10.01.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1433-0458 |
| DOI: | 10.1007/s00106-014-2966-6 |