Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation
Existing methods to improve motor function after stroke include non-specific neuromodulatory approaches. Here the authors use an automated method of analysis of reaching behaviour in rodents to show that optogenetic stimulation of intact corticospinal tract fibres leads to restoration of prior motor...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30 October 2017
|
| In: |
Nature Communications
Year: 2017, Jahrgang: 8 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-017-01090-6 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/s41467-017-01090-6 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41467-017-01090-6 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41467-017-01090-6.pdf 
|
| Verfasserangaben: | A.S. Wahl, U. Büchler, A. Brändli, B. Brattoli, S. Musall, H. Kasper, B.V. Ineichen, F. Helmchen, B. Ommer, M.E. Schwab |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1567299598 | ||
| 003 | DE-627 | ||
| 005 | 20220814060842.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180118s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41467-017-01090-6 |2 doi | |
| 035 | |a (DE-627)1567299598 | ||
| 035 | |a (DE-576)497299593 | ||
| 035 | |a (DE-599)BSZ497299593 | ||
| 035 | |a (OCoLC)1340985918 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 27 |2 sdnb | ||
| 100 | 1 | |a Wahl, Anna-Sophia |d 1985- |e VerfasserIn |0 (DE-588)1013152603 |0 (DE-627)704970570 |0 (DE-576)34661399X |4 aut | |
| 245 | 1 | 0 | |a Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation |c A.S. Wahl, U. Büchler, A. Brändli, B. Brattoli, S. Musall, H. Kasper, B.V. Ineichen, F. Helmchen, B. Ommer, M.E. Schwab |
| 264 | 1 | |c 30 October 2017 | |
| 300 | |a 16 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 18.01.2018 | ||
| 520 | |a Existing methods to improve motor function after stroke include non-specific neuromodulatory approaches. Here the authors use an automated method of analysis of reaching behaviour in rodents to show that optogenetic stimulation of intact corticospinal tract fibres leads to restoration of prior motor functions, rather than compensatory acquisition of new movements. | ||
| 700 | 1 | |a Büchler, Uta |e VerfasserIn |0 (DE-588)1150865377 |0 (DE-627)1011125986 |0 (DE-576)497297620 |4 aut | |
| 700 | 1 | |a Brattoli, Biagio |e VerfasserIn |0 (DE-588)1150865695 |0 (DE-627)1011126354 |0 (DE-576)497297523 |4 aut | |
| 700 | 1 | |a Ommer, Björn |d 1981- |e VerfasserIn |0 (DE-588)1034893106 |0 (DE-627)746457510 |0 (DE-576)382507916 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature Communications |d [London] : Springer Nature, 2010 |g 8(2017) Artikel-Nummer 1187, 16 Seiten |h Online-Ressource |w (DE-627)626457688 |w (DE-600)2553671-0 |w (DE-576)331555905 |x 2041-1723 |7 nnas |a Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation |
| 773 | 1 | 8 | |g volume:8 |g year:2017 |g extent:16 |a Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1038/s41467-017-01090-6 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41467-017-01090-6 |x Verlag |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41467-017-01090-6.pdf |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180118 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 1034893106 |a Ommer, Björn |m 1034893106:Ommer, Björn |d 700000 |d 708070 |e 700000PO1034893106 |e 708070PO1034893106 |k 0/700000/ |k 1/700000/708070/ |p 9 | ||
| 998 | |g 1150865695 |a Brattoli, Biagio |m 1150865695:Brattoli, Biagio |d 700000 |d 708000 |e 700000PB1150865695 |e 708000PB1150865695 |k 0/700000/ |k 1/700000/708000/ |p 4 | ||
| 998 | |g 1150865377 |a Büchler, Uta |m 1150865377:Büchler, Uta |d 700000 |d 708070 |e 700000PB1150865377 |e 708070PB1150865377 |k 0/700000/ |k 1/700000/708070/ |p 2 | ||
| 999 | |a KXP-PPN1567299598 |e 2993066978 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1567299598","language":["eng"],"note":["Gesehen am 18.01.2018"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Wahl, Anna-Sophia","given":"Anna-Sophia","family":"Wahl"},{"display":"Büchler, Uta","roleDisplay":"VerfasserIn","role":"aut","family":"Büchler","given":"Uta"},{"given":"Biagio","family":"Brattoli","role":"aut","display":"Brattoli, Biagio","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Ommer, Björn","given":"Björn","family":"Ommer"}],"title":[{"title":"Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation","title_sort":"Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation"}],"relHost":[{"id":{"eki":["626457688"],"zdb":["2553671-0"],"issn":["2041-1723"]},"origin":[{"publisherPlace":"[London] ; [London]","dateIssuedDisp":"[2010]-","publisher":"Springer Nature ; Nature Publishing Group UK"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Nature Communications","title":"Nature Communications"}],"part":{"year":"2017","extent":"16","text":"8(2017) Artikel-Nummer 1187, 16 Seiten","volume":"8"},"pubHistory":["2010-"],"language":["eng"],"recId":"626457688","type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formationNature Communications","note":["Gesehen am 13.06.24"]}],"physDesc":[{"extent":"16 S."}],"name":{"displayForm":["A.S. Wahl, U. Büchler, A. Brändli, B. Brattoli, S. Musall, H. Kasper, B.V. Ineichen, F. Helmchen, B. Ommer, M.E. Schwab"]},"id":{"doi":["10.1038/s41467-017-01090-6"],"eki":["1567299598"]},"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"30 October 2017"}]} | ||
| SRT | |a WAHLANNASOOPTOGENETI3020 | ||