Novel prognostic markers derived from cardiovascular magnetic resonance imaging in patients with stable chronic coronary artery disease
Background: In patients with coronary artery disease (CAD), risk stratification remains a challenge. Recently, epicardial adipose tissue (EAT) assessed by cardiovascular magnetic resonance imaging (CMRI) has emerged as a new marker in patients with CAD. Thus, we aimed to investigate the association...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
November-December 2015
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| In: |
In vivo
Year: 2015, Jahrgang: 29, Heft: 6, Pages: 737-747 |
| ISSN: | 1791-7549 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://iv.iiarjournals.org/content/29/6/737
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| Verfasserangaben: | Christina Doesch, Jan Jochims, Florian Streitner, Juergen Kuschyk, Ibrahim Akin, Ralf Lehmann, Dirk Lossnitzer, Michael Behnes, Stefan O. Schoenberg, Martin Borggrefe and Theano Papavassiliu |
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| 245 | 1 | 0 | |a Novel prognostic markers derived from cardiovascular magnetic resonance imaging in patients with stable chronic coronary artery disease |c Christina Doesch, Jan Jochims, Florian Streitner, Juergen Kuschyk, Ibrahim Akin, Ralf Lehmann, Dirk Lossnitzer, Michael Behnes, Stefan O. Schoenberg, Martin Borggrefe and Theano Papavassiliu |
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| 520 | |a Background: In patients with coronary artery disease (CAD), risk stratification remains a challenge. Recently, epicardial adipose tissue (EAT) assessed by cardiovascular magnetic resonance imaging (CMRI) has emerged as a new marker in patients with CAD. Thus, we aimed to investigate the association of CMR parameters with all-cause and cardiac mortality in patients with CAD. Patients and Methods: CMRI examination was performed in 260 patients with CAD. Results: In the 40 patients who died, left ventricular (LV) ejection fraction, right ventricular fractioning shortening, LV remodeling index and indexed EAT were significantly reduced, whereas LV mass index, LV end-diastolic volume index, LV end-systolic volume index, LV end-diastolic diameter and the extent of late gadolinium enhancement expressed as a percentage of the maximum possible score to estimate the extent of LGE relative to LV mass (LGE %), were significantly elevated. Using multivariate analysis, age, LV mass index, extent of LGE % and indexed EAT proved to be independently associated with all-cause and cardiac mortality. Conclusion: Age, LV mass index, the extent of LGE % and indexed EAT are independent predictors of mortality that might contribute to a more accurate risk stratification of patients with CAD. | ||
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| 650 | 4 | |a left ventricular mass index | |
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| 650 | 4 | |a stable coronary artery disease | |
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