Image quality of 3rd generation spiral cranial dual-source CT in combination with an advanced model iterative reconstruction technique: a prospective intra-individual comparison study to standard sequential cranial CT using identical radiation dose

Objectives: To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT) spiral cranial CT (cCT) to a sequential 4-slice Multi-Slice-CT (MSCT) while maintaining identical intra-individual radiation dose levels. Methods: 35 patients, who had a non-contrast enhan...

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Hauptverfasser: Wenz, Holger (VerfasserIn) , Maros, Máté E. (VerfasserIn) , Meyer, Mathias (VerfasserIn) , Förster, Alex (VerfasserIn) , Haubenreisser, Holger (VerfasserIn) , Kurth, Stefan (VerfasserIn) , Schönberg, Stefan (VerfasserIn) , Groden, Christoph (VerfasserIn) , Scharf, Johann (VerfasserIn) , Henzler, Thomas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: August 19, 2015
In: PLOS ONE
Year: 2015, Jahrgang: 10, Heft: 8
ISSN:1932-6203
DOI:10.1371/journal.pone.0136054
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pone.0136054
Verlag, kostenfrei, Volltext: http://journals.plos.org.ezproxy.medma.uni-heidelberg.de/plosone/article?id=10.1371/journal.pone.0136054
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Verfasserangaben:Holger Wenz, Máté E. Maros, Mathias Meyer, Alex Förster, Holger Haubenreisser, Stefan Kurth, Stefan O. Schoenberg, Thomas Flohr, Christianne Leidecker, Christoph Groden, Johann Scharf, Thomas Henzler

MARC

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245 1 0 |a Image quality of 3rd generation spiral cranial dual-source CT in combination with an advanced model iterative reconstruction technique  |b a prospective intra-individual comparison study to standard sequential cranial CT using identical radiation dose  |c Holger Wenz, Máté E. Maros, Mathias Meyer, Alex Förster, Holger Haubenreisser, Stefan Kurth, Stefan O. Schoenberg, Thomas Flohr, Christianne Leidecker, Christoph Groden, Johann Scharf, Thomas Henzler 
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520 |a Objectives: To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT) spiral cranial CT (cCT) to a sequential 4-slice Multi-Slice-CT (MSCT) while maintaining identical intra-individual radiation dose levels. Methods: 35 patients, who had a non-contrast enhanced sequential cCT examination on a 4-slice MDCT within the past 12 months, underwent a spiral cCT scan on a 3rd generation DSCT. CTDIvol identical to initial 4-slice MDCT was applied. Data was reconstructed using filtered backward projection (FBP) and 3rd-generation iterative reconstruction (IR) algorithm at 5 different IR strength levels. Two neuroradiologists independently evaluated subjective image quality using a 4-point Likert-scale and objective image quality was assessed in white matter and nucleus caudatus with signal-to-noise ratios (SNR) being subsequently calculated. Results: Subjective image quality of all spiral cCT datasets was rated significantly higher compared to the 4-slice MDCT sequential acquisitions (p<0.05). Mean SNR was significantly higher in all spiral compared to sequential cCT datasets with mean SNR improvement of 61.65% (p*Bonferroni0.05<0.0024). Subjective image quality improved with increasing IR levels. Conclusion: Combination of 3rd-generation DSCT spiral cCT with an advanced model IR technique significantly improves subjective and objective image quality compared to a standard sequential cCT acquisition acquired at identical dose levels. 
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