Modification and quantification of in vivo EROD live-imaging with zebrafish (Danio rerio) embryos to detect both induction and inhibition of CYP1A

The visualization of specific activation of the aryl hydrocarbon receptor (AhR) directly in the zebrafish embryo (Danio rerio) via live-imaging is a reliable tool to investigate the presence of dioxin-like substances in environmental samples. The co-existence of inducers and inhibitors of cytochrome...

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Main Authors: Kais, Britta (Author) , Ottermanns, Richard (Author) , Scheller, Franziska (Author) , Braunbeck, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 15 February 2018
In: The science of the total environment
Year: 2018, Volume: 615, Pages: 330-347
ISSN:1879-1026
DOI:10.1016/j.scitotenv.2017.09.257
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.scitotenv.2017.09.257
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0048969717326098
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Author Notes:Britta Kais, Richard Ottermanns, Franziska Scheller, Thomas Braunbeck
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Modification and quantification of in vivo EROD live-imaging with zebrafish (Danio rerio) embryos to detect both induction and inhibition of CYP1A by Kais, Britta (Author) , Ottermanns, Richard (Author) , Scheller, Franziska (Author) , Braunbeck, Thomas (Author) ,


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Article (Journal)