Breast cancer presentation and therapy in migrant versus native German patients: contrasting and convergent data of a retrospective monocentric study
PurposeThe aim of this study was to identify differences between breast cancer patients with and without migrant background in Germany, especially differences concerning patient characteristics, tumor biology, diagnostics, therapy, and oncological outcome.Patients and methodsIn 99 breast cancer pati...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
4 November 2015
|
| In: |
Archives of gynecology and obstetrics
Year: 2016, Jahrgang: 294, Heft: 1, Pages: 145-152 |
| ISSN: | 1432-0711 |
| DOI: | 10.1007/s00404-015-3938-0 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00404-015-3938-0 Verlag, Volltext: https://link.springer.com/article/10.1007/s00404-015-3938-0 
|
| Verfasserangaben: | Alexandra von Au, Ulrike Weiler, Stefan Stefanovic, Markus Wallwiener, Joerg Heil, Michael Golatta, Joachim Rom, Christof Sohn, Andreas Schneeweiss, Florian Schuetz, Christoph Domschke |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1570654344 | ||
| 003 | DE-627 | ||
| 005 | 20230428184828.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180308s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00404-015-3938-0 |2 doi | |
| 035 | |a (DE-627)1570654344 | ||
| 035 | |a (DE-576)500654344 | ||
| 035 | |a (DE-599)BSZ500654344 | ||
| 035 | |a (OCoLC)1340994019 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Au, Alexandra von |d 1985- |e VerfasserIn |0 (DE-588)1022333909 |0 (DE-627)716953366 |0 (DE-576)362850666 |4 aut | |
| 245 | 1 | 0 | |a Breast cancer presentation and therapy in migrant versus native German patients |b contrasting and convergent data of a retrospective monocentric study |c Alexandra von Au, Ulrike Weiler, Stefan Stefanovic, Markus Wallwiener, Joerg Heil, Michael Golatta, Joachim Rom, Christof Sohn, Andreas Schneeweiss, Florian Schuetz, Christoph Domschke |
| 264 | 1 | |c 4 November 2015 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 08.03.2018 | ||
| 520 | |a PurposeThe aim of this study was to identify differences between breast cancer patients with and without migrant background in Germany, especially differences concerning patient characteristics, tumor biology, diagnostics, therapy, and oncological outcome.Patients and methodsIn 99 breast cancer patients (composed of 50 native, randomly selected Germans and 49 consecutively selected immigrants of Anatolian origin) who were operated due to breast cancer at the Heidelberg University Hospital between the years 2009-2012, relevant information was retrospectively reviewed.ResultsPatients with migrant background were significantly younger at the time of receiving the diagnosis of breast cancer than native German patients with an average age difference of nine years (p < 0.001). Moreover, immigrants needed a second operation for re-excision more frequently than native Germans (45 vs. 20 %, p = 0.01). The medication used for hormone therapy was significantly different between the two cohorts (p = 0.049). Although statistically not significant, a tendency towards difference was observed in six characteristics examined: Premenopausal status, estrogen receptor-positive tumors, multifocal or bilateral tumors, BRCA-1 mutations, and an accompanying carcinoma in situ were more common in patients with migrant background. On the other hand, correspondence was found between both patient groups relating to tumor staging, grading and metastasis as well as surgical, drug, and radiologic therapies employed. Oncologic outcome data were not different either.ConclusionA difference in age between breast cancer patients of diverse ethnic groups has already been described previously. The difference in the frequency of surgical re-excision might be explained by several factors like a young age at first diagnosis, premenopausal status, multifocal tumors and an accompanying carcinoma in situ which were more common in the migrant patients of this study and are known to increase the risk of re-excision. The medication used for hormonal therapy was also different between migrants and native Germans, which might be interpreted by the difference in patients’ age and menopausal status. Of note, however, in the present study, the overall breast cancer outcome did not show any substantial disparity between the different ethnic patient groups investigated. | ||
| 700 | 1 | |a Weiler, Ulrike Karolin |d 1989- |e VerfasserIn |0 (DE-588)1103155490 |0 (DE-627)860772918 |0 (DE-576)470498803 |4 aut | |
| 700 | 1 | |a Stefanovic, Stefan |e VerfasserIn |0 (DE-588)111256117X |0 (DE-627)866525831 |0 (DE-576)476625564 |4 aut | |
| 700 | 1 | |a Wallwiener, Markus |d 1980- |e VerfasserIn |0 (DE-588)134044827 |0 (DE-627)692043934 |0 (DE-576)27468327X |4 aut | |
| 700 | 1 | |a Heil, Jörg |d 1978- |e VerfasserIn |0 (DE-588)132580187 |0 (DE-627)52396160X |0 (DE-576)299238679 |4 aut | |
| 700 | 1 | |a Golatta, Michael |d 1974- |e VerfasserIn |0 (DE-588)132350386 |0 (DE-627)521535727 |0 (DE-576)299091392 |4 aut | |
| 700 | 1 | |a Rom, Joachim |d 1975- |e VerfasserIn |0 (DE-588)130877018 |0 (DE-627)707590604 |0 (DE-576)298390833 |4 aut | |
| 700 | 1 | |a Sohn, Christof |d 1961- |e VerfasserIn |0 (DE-588)131349287 |0 (DE-627)507642902 |0 (DE-576)298422255 |4 aut | |
| 700 | 1 | |a Schneeweiss, Andreas |d 1961- |e VerfasserIn |0 (DE-588)109972554 |0 (DE-627)632849630 |0 (DE-576)327251859 |4 aut | |
| 700 | 1 | |a Schütz, Florian |d 1972- |e VerfasserIn |0 (DE-588)12303387X |0 (DE-627)082307229 |0 (DE-576)293528810 |4 aut | |
| 700 | 1 | |a Domschke, Christoph |d 1982- |e VerfasserIn |0 (DE-588)139103201 |0 (DE-627)703207679 |0 (DE-576)310245095 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Archives of gynecology and obstetrics |d Berlin : Springer, 1987 |g 294(2016), 1, Seite 145-152 |h Online-Ressource |w (DE-627)253390060 |w (DE-600)1458450-5 |w (DE-576)072283270 |x 1432-0711 |7 nnas |a Breast cancer presentation and therapy in migrant versus native German patients contrasting and convergent data of a retrospective monocentric study |
| 773 | 1 | 8 | |g volume:294 |g year:2016 |g number:1 |g pages:145-152 |g extent:8 |a Breast cancer presentation and therapy in migrant versus native German patients contrasting and convergent data of a retrospective monocentric study |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00404-015-3938-0 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://link.springer.com/article/10.1007/s00404-015-3938-0 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180308 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 139103201 |a Domschke, Christoph |m 139103201:Domschke, Christoph |d 910000 |d 910400 |e 910000PD139103201 |e 910400PD139103201 |k 0/910000/ |k 1/910000/910400/ |p 11 |y j | ||
| 998 | |g 12303387X |a Schütz, Florian |m 12303387X:Schütz, Florian |d 910000 |d 910400 |e 910000PS12303387X |e 910400PS12303387X |k 0/910000/ |k 1/910000/910400/ |p 10 | ||
| 998 | |g 109972554 |a Schneeweiss, Andreas |m 109972554:Schneeweiss, Andreas |d 910000 |d 910400 |e 910000PS109972554 |e 910400PS109972554 |k 0/910000/ |k 1/910000/910400/ |p 9 | ||
| 998 | |g 131349287 |a Sohn, Christof |m 131349287:Sohn, Christof |d 910000 |d 910400 |e 910000PS131349287 |e 910400PS131349287 |k 0/910000/ |k 1/910000/910400/ |p 8 | ||
| 998 | |g 130877018 |a Rom, Joachim |m 130877018:Rom, Joachim |d 910000 |d 910400 |e 910000PR130877018 |e 910400PR130877018 |k 0/910000/ |k 1/910000/910400/ |p 7 | ||
| 998 | |g 132350386 |a Golatta, Michael |m 132350386:Golatta, Michael |d 910000 |d 910400 |e 910000PG132350386 |e 910400PG132350386 |k 0/910000/ |k 1/910000/910400/ |p 6 | ||
| 998 | |g 132580187 |a Heil, Jörg |m 132580187:Heil, Jörg |d 910000 |d 910400 |e 910000PH132580187 |e 910400PH132580187 |k 0/910000/ |k 1/910000/910400/ |p 5 | ||
| 998 | |g 134044827 |a Wallwiener, Markus |m 134044827:Wallwiener, Markus |d 910000 |d 910400 |e 910000PW134044827 |e 910400PW134044827 |k 0/910000/ |k 1/910000/910400/ |p 4 | ||
| 998 | |g 111256117X |a Stefanovic, Stefan |m 111256117X:Stefanovic, Stefan |d 910000 |d 910400 |e 910000PS111256117X |e 910400PS111256117X |k 0/910000/ |k 1/910000/910400/ |p 3 | ||
| 998 | |g 1103155490 |a Weiler, Ulrike Karolin |m 1103155490:Weiler, Ulrike Karolin |d 910000 |d 910400 |e 910000PW1103155490 |e 910400PW1103155490 |k 0/910000/ |k 1/910000/910400/ |p 2 | ||
| 998 | |g 1022333909 |a Au, Alexandra von |m 1022333909:Au, Alexandra von |d 910000 |d 910400 |e 910000PA1022333909 |e 910400PA1022333909 |k 0/910000/ |k 1/910000/910400/ |p 1 |x j | ||
| 999 | |a KXP-PPN1570654344 |e 3002129674 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 08.03.2018"],"relHost":[{"pubHistory":["Volume 241, issue 1 (March 1987)-"],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"253390060","disp":"Breast cancer presentation and therapy in migrant versus native German patients contrasting and convergent data of a retrospective monocentric studyArchives of gynecology and obstetrics","titleAlt":[{"title":"Gynecology and obstetrics"}],"language":["eng"],"id":{"issn":["1432-0711"],"zdb":["1458450-5"],"eki":["253390060"]},"part":{"issue":"1","extent":"8","text":"294(2016), 1, Seite 145-152","volume":"294","pages":"145-152","year":"2016"},"physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 10.07.25","Fortsetzung der Druck-Ausgabe"],"origin":[{"dateIssuedDisp":"1987-","publisher":"Springer","publisherPlace":"Berlin ; Heidelberg","dateIssuedKey":"1987"}],"name":{"displayForm":["GG, Deutsche Gesellschaft für Gynäkologie und Geburtshilfe"]},"title":[{"title":"Archives of gynecology and obstetrics","title_sort":"Archives of gynecology and obstetrics"}]}],"id":{"doi":["10.1007/s00404-015-3938-0"],"eki":["1570654344"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"8 S."}],"title":[{"title_sort":"Breast cancer presentation and therapy in migrant versus native German patients","subtitle":"contrasting and convergent data of a retrospective monocentric study","title":"Breast cancer presentation and therapy in migrant versus native German patients"}],"language":["eng"],"origin":[{"dateIssuedKey":"2016","dateIssuedDisp":"4 November 2015"}],"name":{"displayForm":["Alexandra von Au, Ulrike Weiler, Stefan Stefanovic, Markus Wallwiener, Joerg Heil, Michael Golatta, Joachim Rom, Christof Sohn, Andreas Schneeweiss, Florian Schuetz, Christoph Domschke"]},"recId":"1570654344","person":[{"family":"Au","given":"Alexandra von","display":"Au, Alexandra von","role":"aut"},{"role":"aut","display":"Weiler, Ulrike Karolin","given":"Ulrike Karolin","family":"Weiler"},{"family":"Stefanovic","display":"Stefanovic, Stefan","given":"Stefan","role":"aut"},{"role":"aut","given":"Markus","display":"Wallwiener, Markus","family":"Wallwiener"},{"role":"aut","given":"Jörg","display":"Heil, Jörg","family":"Heil"},{"family":"Golatta","display":"Golatta, Michael","given":"Michael","role":"aut"},{"family":"Rom","display":"Rom, Joachim","given":"Joachim","role":"aut"},{"role":"aut","given":"Christof","display":"Sohn, Christof","family":"Sohn"},{"role":"aut","display":"Schneeweiss, Andreas","given":"Andreas","family":"Schneeweiss"},{"given":"Florian","display":"Schütz, Florian","family":"Schütz","role":"aut"},{"role":"aut","family":"Domschke","given":"Christoph","display":"Domschke, Christoph"}]} | ||
| SRT | |a AUALEXANDRBREASTCANC4201 | ||