Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen
Cytokines are coordinators of immune homeostasis. Evidence for the participation of cytokines in neurogenic inflammation, peripheral and central sensitization and hyperalgesia as well as for induction of inflammatory immune responses by pain-related catastrophizing is well documented. A disproportio...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Deutsch |
| Veröffentlicht: |
04 July 2012
|
| In: |
Der Schmerz
Year: 2012, Jahrgang: 26, Heft: 4, Pages: 383-388 |
| ISSN: | 1432-2129 |
| DOI: | 10.1007/s00482-012-1153-5 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00482-012-1153-5
|
| Verfasserangaben: | C. Ahrens, M. Schiltenwolf, H. Wang |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1571647864 | ||
| 003 | DE-627 | ||
| 005 | 20220814103533.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180403s2012 xx |||||o 00| ||ger c | ||
| 024 | 7 | |a 10.1007/s00482-012-1153-5 |2 doi | |
| 035 | |a (DE-627)1571647864 | ||
| 035 | |a (DE-576)501647864 | ||
| 035 | |a (DE-599)BSZ501647864 | ||
| 035 | |a (OCoLC)1341001019 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a ger | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Ahrens, Carsten |d 1974- |e VerfasserIn |0 (DE-588)1016627920 |0 (DE-627)705558142 |0 (DE-576)349887675 |4 aut | |
| 245 | 1 | 0 | |a Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen |c C. Ahrens, M. Schiltenwolf, H. Wang |
| 246 | 3 | 3 | |a Cytokines in psychoneuroendocrine immunological context of nonspecific musculoskeletal pain |
| 264 | 1 | |c 04 July 2012 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 03.04.2018 | ||
| 520 | |a Cytokines are coordinators of immune homeostasis. Evidence for the participation of cytokines in neurogenic inflammation, peripheral and central sensitization and hyperalgesia as well as for induction of inflammatory immune responses by pain-related catastrophizing is well documented. A disproportion of proinflammatory and anti-inflammatory cytokines is known to be a contributory cause of pain and pain behavior. Embedded into psychoneuroendocrine immunological feedback control systems cytokines are able to perpetuate a virtuous circle between local inflammation and systemic pain behavior (pain/sickness behavior) thus contributing to chronification of nonspecific musculoskeletal pain.In this model avoidance and pain-related nonrecognition as key components of systemic pain behavior lead to maintenance of the virtuous circle by generating of a local inflammation with local and systemic consequences. This model can explain the success of established therapy concepts from the point of view of psychoneuroimmunology, such as fear avoidance, which are effectively used as principal components in multimodal pain therapy. | ||
| 650 | 4 | |a Central Nervous System | |
| 650 | 4 | |a Combined Modality Therapy | |
| 650 | 4 | |a Cytokines | |
| 650 | 4 | |a Homeostasis | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Hydrocortisone | |
| 650 | 4 | |a Hypothalamo-Hypophyseal System | |
| 650 | 4 | |a Illness Behavior | |
| 650 | 4 | |a Musculoskeletal Pain | |
| 650 | 4 | |a Neuroimmunomodulation | |
| 650 | 4 | |a Nociceptors | |
| 650 | 4 | |a Pituitary-Adrenal System | |
| 650 | 4 | |a Psychophysiologic Disorders | |
| 650 | 4 | |a Stress, Psychological | |
| 700 | 1 | |a Schiltenwolf, Marcus |d 1959- |e VerfasserIn |0 (DE-588)11138673X |0 (DE-627)515952303 |0 (DE-576)289700841 |4 aut | |
| 700 | 1 | |a Wang, Haili |e VerfasserIn |0 (DE-588)1060237024 |0 (DE-627)799335274 |0 (DE-576)41633573X |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Der Schmerz |d Berlin : Springer, 1987 |g 26(2012), 4, Seite 383-388 |h Online-Ressource |w (DE-627)254639194 |w (DE-600)1463039-4 |w (DE-576)074531867 |x 1432-2129 |7 nnas |a Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen |
| 773 | 1 | 8 | |g volume:26 |g year:2012 |g number:4 |g pages:383-388 |g extent:6 |a Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00482-012-1153-5 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180403 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 1060237024 |a Wang, Haili |m 1060237024:Wang, Haili |d 910000 |d 911460 |e 910000PW1060237024 |e 911460PW1060237024 |k 0/910000/ |k 1/910000/911460/ |p 3 |y j | ||
| 998 | |g 11138673X |a Schiltenwolf, Marcus |m 11138673X:Schiltenwolf, Marcus |d 910000 |d 911460 |e 910000PS11138673X |e 911460PS11138673X |k 0/910000/ |k 1/910000/911460/ |p 2 | ||
| 998 | |g 1016627920 |a Ahrens, Carsten |m 1016627920:Ahrens, Carsten |d 910000 |d 911460 |e 910000PA1016627920 |e 911460PA1016627920 |k 0/910000/ |k 1/910000/911460/ |p 1 |x j | ||
| 999 | |a KXP-PPN1571647864 |e 300478534X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1571647864","relHost":[{"id":{"issn":["1432-2129"],"zdb":["1463039-4"],"eki":["254639194"]},"physDesc":[{"extent":"Online-Ressource"}],"name":{"displayForm":["in Zusammenarbeit mit Schmerztherapeutisches Kolloquium ..."]},"recId":"254639194","type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler SchmerzenDer Schmerz","title":[{"subtitle":"Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie","title_sort":"Schmerz","title":"Der Schmerz"}],"pubHistory":["1.1987 -"],"note":["Gesehen am 23.11.06"],"origin":[{"dateIssuedDisp":"1987-","publisher":"Springer ; Springer","dateIssuedKey":"1987","publisherPlace":"Berlin ; Heidelberg ; Berlin ; Heidelberg ; New York, NY"}],"titleAlt":[{"title":"Organ von: Deutsche Gesellschaft zum Studium des Schmerzes e.V., Österreichische Schmerzgesellschaft (ÖSG), Deutsche Interdisziplinäre Vereinigung für Schmerz"}],"part":{"issue":"4","text":"26(2012), 4, Seite 383-388","year":"2012","pages":"383-388","volume":"26","extent":"6"},"language":["ger"]}],"name":{"displayForm":["C. Ahrens, M. Schiltenwolf, H. Wang"]},"physDesc":[{"extent":"6 S."}],"id":{"eki":["1571647864"],"doi":["10.1007/s00482-012-1153-5"]},"note":["Gesehen am 03.04.2018"],"origin":[{"dateIssuedDisp":"04 July 2012","dateIssuedKey":"2012"}],"title":[{"title":"Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen","title_sort":"Zytokine im psychoneuroendokrin-immunologischen Kontext unspezifischer muskuloskeletaler Schmerzen"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["ger"],"titleAlt":[{"title":"Cytokines in psychoneuroendocrine immunological context of nonspecific musculoskeletal pain"}],"person":[{"display":"Ahrens, Carsten","family":"Ahrens","role":"aut","given":"Carsten"},{"given":"Marcus","role":"aut","family":"Schiltenwolf","display":"Schiltenwolf, Marcus"},{"family":"Wang","display":"Wang, Haili","role":"aut","given":"Haili"}]} | ||
| SRT | |a AHRENSCARSZYTOKINEIM0420 | ||