Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP)
Objectives The purpose of our study was to assess proton density (PD) and T2 relaxation time of usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) and to evaluate their utility in differentiating the two patterns. Furthermore, we aim to investigate whether these two par...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
May 16, 2017
|
| In: |
PLOS ONE
Year: 2017, Volume: 12, Issue: 5, Pages: 1-11 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0177689 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pone.0177689 Verlag, kostenfrei, Volltext: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177689 
|
| Author Notes: | Maria T. A. Buzan, Andreas Wetscherek, Claus Peter Heussel, Michael Kreuter, Felix J. Herth, Arne Warth, Hans-Ulrich Kauczor, Carmen Monica Pop, Julien Dinkel |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1571670599 | ||
| 003 | DE-627 | ||
| 005 | 20230426124229.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180404s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0177689 |2 doi | |
| 035 | |a (DE-627)1571670599 | ||
| 035 | |a (DE-576)501670599 | ||
| 035 | |a (DE-599)BSZ501670599 | ||
| 035 | |a (OCoLC)1341001534 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Buzan, Maria Teodora |e VerfasserIn |0 (DE-588)111521781X |0 (DE-627)869540300 |0 (DE-576)477676308 |4 aut | |
| 245 | 1 | 0 | |a Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP) |c Maria T. A. Buzan, Andreas Wetscherek, Claus Peter Heussel, Michael Kreuter, Felix J. Herth, Arne Warth, Hans-Ulrich Kauczor, Carmen Monica Pop, Julien Dinkel |
| 264 | 1 | |c May 16, 2017 | |
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 20.12.2020 | ||
| 520 | |a Objectives The purpose of our study was to assess proton density (PD) and T2 relaxation time of usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) and to evaluate their utility in differentiating the two patterns. Furthermore, we aim to investigate whether these two parameters could help differentiate active-inflammatory and stable-fibrotic lesions in NSIP. Methods 32 patients (mean age: 69 years; M:F, 1:1) with pathologically proven disease (UIP:NSIP, 1:1), underwent thoracic thin-section multislice CT scan and 1.5T MRI. A total of 437 regions-of-interest (ROIs) were classified at CT as advanced, moderate or mild alterations. Based on multi-echo single-shot TSE sequence acquired at five echo times, with breath-holding at end-expiration and ECG-triggering, entire lung T2 and PD maps were generated from each subject. The T2 relaxation time and the respective signal intensity were quantified by performing a ROI measurement on the T2 and PD maps in the corresponding CT selected areas of the lung. Results UIP and NSIP regional patterns could not be differentiated by T2 relaxation times or PD values alone. Overall, a strong positive correlation was found between T2 relaxation and PD in NSIP, r = 0.64, p<0.001; however, this correlation was weak in UIP, r = 0.20, p = 0.01. T2 relaxation showed significant statistical difference between active-inflammatory and stable-fibrotic NSIP regions at all levels, p<0.05, while for the analysis of ventral lesions PD proved no statistical difference, p>0.05. Conclusions T2 relaxation times and PD values may provide helpful quantitative information for differentiating NSIP from UIP pattern. These parameters have the potential to differentiate active-inflammatory and stable-fibrotic lesions in NSIP. | ||
| 650 | 4 | |a Computed axial tomography | |
| 650 | 4 | |a Fibrosis | |
| 650 | 4 | |a Lesions | |
| 650 | 4 | |a Magnetic resonance imaging | |
| 650 | 4 | |a NMR relaxation | |
| 650 | 4 | |a Pneumonia | |
| 650 | 4 | |a Pulmonary imaging | |
| 650 | 4 | |a Relaxation time | |
| 700 | 1 | |a Wetscherek, Andreas |e VerfasserIn |0 (DE-588)1038279011 |0 (DE-627)756915430 |0 (DE-576)392262703 |4 aut | |
| 700 | 1 | |a Heußel, Claus Peter |e VerfasserIn |0 (DE-588)1048631389 |0 (DE-627)780769422 |0 (DE-576)40288146X |4 aut | |
| 700 | 1 | |a Kreuter, Michael |d 1972- |e VerfasserIn |0 (DE-588)122645995 |0 (DE-627)082066795 |0 (DE-576)293362742 |4 aut | |
| 700 | 1 | |a Herth, Felix |e VerfasserIn |0 (DE-588)1016095236 |0 (DE-627)705477568 |0 (DE-576)351509925 |4 aut | |
| 700 | 1 | |a Warth, Arne |d 1979- |e VerfasserIn |0 (DE-588)132646145 |0 (DE-627)524716927 |0 (DE-576)260019755 |4 aut | |
| 700 | 1 | |a Kauczor, Hans-Ulrich |d 1962- |e VerfasserIn |0 (DE-588)139267123 |0 (DE-627)70327113X |0 (DE-576)310955327 |4 aut | |
| 700 | 1 | |a Dinkel, Julien |d 1978- |e VerfasserIn |0 (DE-588)140755632 |0 (DE-627)621592773 |0 (DE-576)320647374 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PLOS ONE |d San Francisco, California, US : PLOS, 2006 |g 12(2017,5) Artikel-Nummer e0177689, 11 Seiten |h Online-Ressource |w (DE-627)523574592 |w (DE-600)2267670-3 |w (DE-576)281331979 |x 1932-6203 |7 nnas |a Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP) |
| 773 | 1 | 8 | |g volume:12 |g year:2017 |g number:5 |g pages:1-11 |g extent:11 |a Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP) |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1371/journal.pone.0177689 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177689 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180404 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 140755632 |a Dinkel, Julien |m 140755632:Dinkel, Julien |d 910000 |d 911400 |e 910000PD140755632 |e 911400PD140755632 |k 0/910000/ |k 1/910000/911400/ |p 9 |y j | ||
| 998 | |g 139267123 |a Kauczor, Hans-Ulrich |m 139267123:Kauczor, Hans-Ulrich |d 910000 |d 911400 |e 910000PK139267123 |e 911400PK139267123 |k 0/910000/ |k 1/910000/911400/ |p 7 | ||
| 998 | |g 132646145 |a Warth, Arne |m 132646145:Warth, Arne |d 910000 |d 912000 |e 910000PW132646145 |e 912000PW132646145 |k 0/910000/ |k 1/910000/912000/ |p 6 | ||
| 998 | |g 1016095236 |a Herth, Felix |m 1016095236:Herth, Felix |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PH1016095236 |e 950000PH1016095236 |e 950900PH1016095236 |e 50000PH1016095236 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 5 | ||
| 998 | |g 122645995 |a Kreuter, Michael |m 122645995:Kreuter, Michael |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PK122645995 |e 950000PK122645995 |e 950900PK122645995 |e 50000PK122645995 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 4 | ||
| 998 | |g 1048631389 |a Heußel, Claus Peter |m 1048631389:Heußel, Claus Peter |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PH1048631389 |e 950000PH1048631389 |e 950900PH1048631389 |e 50000PH1048631389 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 3 | ||
| 998 | |g 111521781X |a Buzan, Maria Teodora |m 111521781X:Buzan, Maria Teodora |d 910000 |d 911400 |e 910000PB111521781X |e 911400PB111521781X |k 0/910000/ |k 1/910000/911400/ |p 1 |x j | ||
| 999 | |a KXP-PPN1571670599 |e 3004846098 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1571670599","type":{"media":"Online-Ressource","bibl":"article-journal"},"name":{"displayForm":["Maria T. A. Buzan, Andreas Wetscherek, Claus Peter Heussel, Michael Kreuter, Felix J. Herth, Arne Warth, Hans-Ulrich Kauczor, Carmen Monica Pop, Julien Dinkel"]},"language":["eng"],"id":{"doi":["10.1371/journal.pone.0177689"],"eki":["1571670599"]},"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"May 16, 2017"}],"note":["Gesehen am 20.12.2020"],"physDesc":[{"extent":"11 S."}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"note":["Schreibweise des Titels bis 2012: PLoS ONE","Gesehen am 20.03.19"],"origin":[{"publisher":"PLOS ; PLoS","dateIssuedDisp":"2006-","dateIssuedKey":"2006","publisherPlace":"San Francisco, California, US ; Lawrence, Kan."}],"id":{"eki":["523574592"],"issn":["1932-6203"],"zdb":["2267670-3"]},"pubHistory":["1.2006 -"],"name":{"displayForm":["Public Library of Science"]},"recId":"523574592","title":[{"title":"PLOS ONE","title_sort":"PLOS ONE"}],"corporate":[{"display":"Public Library of Science","role":"isb"}],"part":{"volume":"12","year":"2017","extent":"11","pages":"1-11","text":"12(2017,5) Artikel-Nummer e0177689, 11 Seiten","issue":"5"},"disp":"Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP)PLOS ONE","type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"]}],"person":[{"display":"Buzan, Maria Teodora","role":"aut","family":"Buzan","given":"Maria Teodora"},{"family":"Wetscherek","given":"Andreas","role":"aut","display":"Wetscherek, Andreas"},{"role":"aut","display":"Heußel, Claus Peter","given":"Claus Peter","family":"Heußel"},{"display":"Kreuter, Michael","role":"aut","given":"Michael","family":"Kreuter"},{"family":"Herth","given":"Felix","role":"aut","display":"Herth, Felix"},{"family":"Warth","given":"Arne","role":"aut","display":"Warth, Arne"},{"display":"Kauczor, Hans-Ulrich","role":"aut","given":"Hans-Ulrich","family":"Kauczor"},{"display":"Dinkel, Julien","role":"aut","given":"Julien","family":"Dinkel"}],"title":[{"title":"Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP)","title_sort":"Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP)"}]} | ||
| SRT | |a BUZANMARIATEXTUREANA1620 | ||