Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma

Meningioma is the most common primary brain tumor and carries a substantial risk of local recurrence. Methylation profiles of meningioma and their clinical implications are not well understood. We hypothesized that aggressive meningiomas have unique DNA methylation patterns that could be used to bet...

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Main Authors: Olar, Adriana (Author) , Jones, David T. W. (Author) , Pfister, Stefan (Author)
Format: Article (Journal)
Language:English
Published: 27 January 2017
In: Acta neuropathologica
Year: 2017, Volume: 133, Issue: 3, Pages: 431-444
ISSN:1432-0533
DOI:10.1007/s00401-017-1678-x
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s00401-017-1678-x
Verlag, Volltext: https://link.springer.com/article/10.1007/s00401-017-1678-x
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Author Notes:Adriana Olar, Khalida M. Wani, Charmaine D. Wilson, Gelareh Zadeh, Franco DeMonte, David T.W. Jones, Stefan M. Pfister, Erik P. Sulman, Kenneth D. Aldape

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