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Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia

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ATP-regulated potassium channels (KATP) regulate pulmonary vascular tone and are involved in hypoxic pulmonary vasoconstriction (HPV). In patients with inflammation like sepsis or ARDS, HPV is impaired, resulting in a ventilation-perfusion mismatch and hypoxia. Since increase of vascular KATP channe...

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Main Authors: Turzo, Maurizio (Author) , Lasitschka, Felix (Author) , Weigand, Markus A. (Author) , Busch, Cornelius (Author)
Format: Article (Journal) Chapter/Article
Language:English
Published: 13 February 2018
In: Increased IL-17RA and IL-17RC in end-stage COPD and the contribution to mast cell secretion of FGF-2 and VEGF
Year: 2018, Volume: 19
DOI:10.1186/s12931-018-0735-x
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12931-018-0735-x
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12931-018-0735-x
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Author Notes:Maurizio Turzo, Julian Vaith, Felix Lasitschka, Markus A. Weigand and Cornelius J. Busch
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Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia by Turzo, Maurizio (Author) , Vaith, Julian (Author) , Lasitschka, Felix (Author) , Weigand, Markus A. (Author) , Busch, Cornelius (Author) ,

BioMed Central 2018

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