HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens

Arrayed high-throughput screens (HTS) cover a broad range of applications using RNAi or small molecules as perturbations and specialized software packages for statistical analysis have become available. However, exploratory data analysis and integration of screening results has remained challenging...

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Hauptverfasser: Scheeder, Christian (VerfasserIn) , Heigwer, Florian (VerfasserIn) , Boutros, Michael (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2017
In: Bioinformatics
Year: 2017, Jahrgang: 33, Heft: 18, Pages: 2960-2962
ISSN:1367-4811
DOI:10.1093/bioinformatics/btx319
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1093/bioinformatics/btx319
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Verfasserangaben:Christian Scheeder, Florian Heigwer and Michael Boutros
Beschreibung
Zusammenfassung:Arrayed high-throughput screens (HTS) cover a broad range of applications using RNAi or small molecules as perturbations and specialized software packages for statistical analysis have become available. However, exploratory data analysis and integration of screening results has remained challenging due to the size of the data sets and the lack of user-friendly tools for interpretation and visualization of screening results. Here we present HTSvis, a web application to interactively visualize raw data, perform quality control and assess screening results from single to multi-channel measurements such as image-based screens. Per well aggregated raw and analyzed data of various assay types and scales can be loaded in a generic tabular format.
Beschreibung:Gesehen am 17.04.2018
Advance access publication date: 15 May 2017
Beschreibung:Online Resource
ISSN:1367-4811
DOI:10.1093/bioinformatics/btx319