Rheological and biological properties of a hydrogel support for cells intended for intervertebral disc repair
Cell-based approaches towards restoration of prolapsed or degenerated intervertebral discs are hampered by a lack of measures for safe administration and placement of cell suspensions within a treated disc. In order to overcome these risks, a serum albumin-based hydrogel has been developed that poly...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 April 2012
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| In: |
BMC musculoskeletal disorders
Year: 2012, Volume: 13 |
| ISSN: | 1471-2474 |
| DOI: | 10.1186/1471-2474-13-54 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1471-2474-13-54 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1471-2474-13-54 |
| Author Notes: | Karin Benz, Claudia Stippich, Claudia Osswald, Christoph Gaissmaier, Nicolas Lembert, Andreas Badke, Eric Steck, Wilhelm K. Aicher, Juergen A. Mollenhauer |
| Summary: | Cell-based approaches towards restoration of prolapsed or degenerated intervertebral discs are hampered by a lack of measures for safe administration and placement of cell suspensions within a treated disc. In order to overcome these risks, a serum albumin-based hydrogel has been developed that polymerizes after injection and anchors the administered cell suspension within the tissue. |
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| Item Description: | Gesehen am 17.04.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1471-2474 |
| DOI: | 10.1186/1471-2474-13-54 |