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A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation

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Hydrogen peroxide (H2O2) acts as a signaling messenger by triggering the reversible oxidation of redox-regulated proteins. It remains unclear how proteins can be oxidized by signaling levels of H2O2 in the presence of peroxiredoxins, which are highly efficient peroxide scavengers. Here we show that...

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Bibliographic Details
Main Authors: Stöcker, Sarah (Author) , Maurer, Michael (Author) , Ruppert, Thomas (Author) , Dick, Tobias P. (Author)
Format: Article (Journal)
Language:English
Published: 2018
In: Nature chemical biology
Year: 2017, Volume: 14, Issue: 2, Pages: 148-155
ISSN:1552-4469
DOI:10.1038/nchembio.2536
Online Access:Verlag, Volltext: http://dx.doi.org/10.1038/nchembio.2536
Verlag, Volltext: https://www.nature.com/articles/nchembio.2536
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Author Notes:Sarah Stöcker, Michael Maurer, Thomas Ruppert & Tobias P. Dick
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Comparing the efficacy and selectivity of Ck2 inhibitors: a phosphoproteomics approach by Borgo, Christian (Author) , Cesaro, Luca (Author) , Hirota, Tsuyoshi (Author) , Kuwata, Keiko (Author) , D’Amore, Claudio (Author) , Ruppert, Thomas (Author) , Blatnik, Renata (Author) , Salvi, Mauro (Author) , Pinna, Lorenzo A. (Author) ,


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