A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation
Hydrogen peroxide (H2O2) acts as a signaling messenger by triggering the reversible oxidation of redox-regulated proteins. It remains unclear how proteins can be oxidized by signaling levels of H2O2 in the presence of peroxiredoxins, which are highly efficient peroxide scavengers. Here we show that...
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| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2018
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| In: |
Nature chemical biology
Year: 2017, Jahrgang: 14, Heft: 2, Pages: 148-155 |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/nchembio.2536 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1038/nchembio.2536 Verlag, Volltext: https://www.nature.com/articles/nchembio.2536 |
| Verfasserangaben: | Sarah Stöcker, Michael Maurer, Thomas Ruppert & Tobias P. Dick |
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