Liver-specific overexpression of matrix metalloproteinase 9 (MMP-9) in transgenic mice accelerates development of hepatocellular carcinoma
Matrix metalloproteinase-9 (MMP-9) plays a central role in tumor invasion and development of metastases. Expression of MMP-9 had been shown in human hepatocellular carcinomas (HCCs). However, it remained unclear whether MMP-9 could influence development of HCC. In order to address this issue, we gen...
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| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Molecular carcinogenesis
Year: 2012, Volume: 51, Issue: 6, Pages: 439-448 |
| ISSN: | 1098-2744 |
| DOI: | 10.1002/mc.20809 |
| Online Access: | Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1002/mc.20809
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| Author Notes: | Florian R. Thieringer, Thorsten Maass, Bianca Anthon, Erik Meyer, Peter Schirmacher, Thomas Longerich, Peter R. Galle, Stephan Kanzler, and Andreas Teufel |