Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography: an updated and comprehensive meta-analysis and systematic review
BACKGROUND AND AIM: This systematic review with meta-analysis sought to determine the strength of evidence for effects of antioxidants (AO) such as N-acetyl cysteine (NAC), vitamin C, vitamin E, and alpha-lipoic acid on the incidence of contrast-in-duced nephropathy (CIN), requirement for haemodialy...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
7 January 2016
|
| In: |
Kardiologia polska
Year: 2016, Jahrgang: 74, Heft: 7, Pages: 610-626 |
| ISSN: | 1897-4279 |
| DOI: | 10.5603/KP.a2016.0007 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.5603/KP.a2016.0007
|
| Verfasserangaben: | Sadeq Ali-Hasan-Al-Saegh, Seyed Jalil Mirhosseini, Zahra Ghodratipour, Zahra Sarafan-Chaharsoughi, Ali Mohammad Dehghan, Elham Rahimizadeh, Azadeh Shahidzadeh, Mohammad Reza Lotfaliani, Farbod Sedaghat-Hamedani, Elham Kayvanpour, Anton Sabashnikov, Aron-Frederik Popov |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1572360496 | ||
| 003 | DE-627 | ||
| 005 | 20230426124301.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180425s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.5603/KP.a2016.0007 |2 doi | |
| 035 | |a (DE-627)1572360496 | ||
| 035 | |a (DE-576)502360496 | ||
| 035 | |a (DE-599)BSZ502360496 | ||
| 035 | |a (OCoLC)1341007551 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Ali-Hasan-Al-Saegh, Sadeq |e VerfasserIn |0 (DE-588)1156676185 |0 (DE-627)1019516240 |0 (DE-576)502363193 |4 aut | |
| 245 | 1 | 0 | |a Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography |b an updated and comprehensive meta-analysis and systematic review |c Sadeq Ali-Hasan-Al-Saegh, Seyed Jalil Mirhosseini, Zahra Ghodratipour, Zahra Sarafan-Chaharsoughi, Ali Mohammad Dehghan, Elham Rahimizadeh, Azadeh Shahidzadeh, Mohammad Reza Lotfaliani, Farbod Sedaghat-Hamedani, Elham Kayvanpour, Anton Sabashnikov, Aron-Frederik Popov |
| 264 | 1 | |c 7 January 2016 | |
| 300 | |a 17 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 25.04.2018 | ||
| 520 | |a BACKGROUND AND AIM: This systematic review with meta-analysis sought to determine the strength of evidence for effects of antioxidants (AO) such as N-acetyl cysteine (NAC), vitamin C, vitamin E, and alpha-lipoic acid on the incidence of contrast-in-duced nephropathy (CIN), requirement for haemodialysis, level of serum creatinine, and mortality after coronary angiography. METHODS AND RESULTS: After Medline, Embase, Elsevier, Sciences online database, and Google Scholar literature searches, studies with randomised controlled design were selected for the meta-analysis. The effect sizes measured were odds ratio (OR) for categorical variables and standard mean difference (SMD) with 95% confidence interval (CI) for calculating differences between mean changes of serum creatinine in intervention and control groups. A value of p < 0.1 for Q test or I2 > 50% indicated significant heterogeneity between the studies. Literature search of all major databases retrieved 2350 studies. After screening, a total of 49 trials were identified that reported outcomes. Pooled treatment effect analysis revealed that NAC (OR of 0.79; 95% CI 0.69-0.9; p = 0.000), vitamin C (0.63; 95% CI 0.45-0.89; p = 0.000), and vitamin E (OR of 0.5; 95% CI 0.27-0.92; p = 0.026) could significantly reduce the incidence of CIN. NAC (SMD of -0.119; 95% CI -0.191 - 0.046; p = 0.000), but not vitamin C (SMD of -0.08; 95% CI -0.22-0.04; p = 0.1) and vitamin E (-0.25; 95% CI -0.46-0.05; p = 0.1), could significantly reduce mean levels of serum creatinine. Nevertheless, AO could not reduce the incidence of mortality, with an OR of 0.94 (95% CI 0.69-1.28; p = 0.7). CONCLUSIONS: Overall, antioxidants such as NAC, vitamin C, and vitamin E can reduce the incidence of CIN, while only NAC might be able to significantly lower serum creatinine levels. There is no impact of AO supplementation on mortality. | ||
| 650 | 4 | |a Aged | |
| 650 | 4 | |a alpha-lipoic | |
| 650 | 4 | |a antioxidant | |
| 650 | 4 | |a Antioxidants | |
| 650 | 4 | |a Contrast Media | |
| 650 | 4 | |a contrast-induced nephropathy | |
| 650 | 4 | |a coronary angiography | |
| 650 | 4 | |a Coronary Angiography | |
| 650 | 4 | |a Dietary Supplements | |
| 650 | 4 | |a Female | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Incidence | |
| 650 | 4 | |a Kidney Diseases | |
| 650 | 4 | |a Kidney Function Tests | |
| 650 | 4 | |a Male | |
| 650 | 4 | |a Middle Aged | |
| 650 | 4 | |a N-acetyl cysteine | |
| 650 | 4 | |a vitamin C | |
| 650 | 4 | |a vitamin E | |
| 700 | 1 | |a Sedaghat-Hamedani, Farbod |d 1984- |e VerfasserIn |0 (DE-588)102545488X |0 (DE-627)722303106 |0 (DE-576)370367138 |4 aut | |
| 700 | 1 | |a Kayvanpour, Elham |d 1984- |e VerfasserIn |0 (DE-588)1033468983 |0 (DE-627)741277573 |0 (DE-576)381064247 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Kardiologia polska |d Poznań : Termedia Wydawn., 2003 |g 74(2016), 7, Seite 610-626 |h Online-Ressource |w (DE-627)353260401 |w (DE-600)2086367-6 |w (DE-576)281214654 |x 1897-4279 |7 nnas |a Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography an updated and comprehensive meta-analysis and systematic review |
| 773 | 1 | 8 | |g volume:74 |g year:2016 |g number:7 |g pages:610-626 |g extent:17 |a Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography an updated and comprehensive meta-analysis and systematic review |
| 856 | 4 | 0 | |u http://dx.doi.org/10.5603/KP.a2016.0007 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180425 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1033468983 |a Kayvanpour, Elham |m 1033468983:Kayvanpour, Elham |d 910000 |d 910100 |e 910000PK1033468983 |e 910100PK1033468983 |k 0/910000/ |k 1/910000/910100/ |p 10 | ||
| 998 | |g 102545488X |a Sedaghat-Hamedani, Farbod |m 102545488X:Sedaghat-Hamedani, Farbod |d 910000 |d 910100 |e 910000PS102545488X |e 910100PS102545488X |k 0/910000/ |k 1/910000/910100/ |p 9 | ||
| 999 | |a KXP-PPN1572360496 |e 3007062438 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"id":{"eki":["353260401"],"zdb":["2086367-6"],"issn":["1897-4279"]},"disp":"Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography an updated and comprehensive meta-analysis and systematic reviewKardiologia polska","origin":[{"publisher":"Termedia Wydawn. ; Państwowy Zakład Wydawn. Lekarskich","dateIssuedDisp":"2003-","publisherPlace":"Poznań ; Warszawa","dateIssuedKey":"2003"}],"corporate":[{"role":"isb","display":"Polskie Towarzystwo Kardiologiczne"}],"pubHistory":["Nachgewiesen 58/59.2003 - 62/63.2005; 64.2006 -"],"note":["Gesehen am 08.12.10"],"title":[{"title":"Kardiologia polska","subtitle":" = Polish heart journal : organ Polskiego Towarzystwa Kardiologicznego","title_sort":"Kardiologia polska"}],"titleTranslated":[{"translated":"Polish heart journal"}],"recId":"353260401","type":{"bibl":"periodical","media":"Online-Ressource"},"language":["pol","eng"],"part":{"extent":"17","pages":"610-626","year":"2016","issue":"7","text":"74(2016), 7, Seite 610-626","volume":"74"},"physDesc":[{"extent":"Online-Ressource"}]}],"title":[{"title":"Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography","title_sort":"Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography","subtitle":"an updated and comprehensive meta-analysis and systematic review"}],"physDesc":[{"extent":"17 S."}],"language":["eng"],"note":["Gesehen am 25.04.2018"],"person":[{"display":"Ali-Hasan-Al-Saegh, Sadeq","role":"aut","family":"Ali-Hasan-Al-Saegh","given":"Sadeq"},{"given":"Farbod","role":"aut","family":"Sedaghat-Hamedani","display":"Sedaghat-Hamedani, Farbod"},{"given":"Elham","family":"Kayvanpour","role":"aut","display":"Kayvanpour, Elham"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1572360496","id":{"doi":["10.5603/KP.a2016.0007"],"eki":["1572360496"]},"origin":[{"dateIssuedKey":"2016","dateIssuedDisp":"7 January 2016"}],"name":{"displayForm":["Sadeq Ali-Hasan-Al-Saegh, Seyed Jalil Mirhosseini, Zahra Ghodratipour, Zahra Sarafan-Chaharsoughi, Ali Mohammad Dehghan, Elham Rahimizadeh, Azadeh Shahidzadeh, Mohammad Reza Lotfaliani, Farbod Sedaghat-Hamedani, Elham Kayvanpour, Anton Sabashnikov, Aron-Frederik Popov"]}} | ||
| SRT | |a ALIHASANALPROTECTIVE7201 | ||