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Depletion of trypanosome CTR9 leads to gene expression defects

The Paf complex of Opisthokonts and plants contains at least five subunits: Paf1, Cdc73, Rtf1, Ctr9, and Leo1. Mutations in, or loss of Paf complex subunits have been shown to cause defects in histone modification, mRNA polyadenylation, and transcription by RNA polymerase I and RNA polymerase II. We...

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Main Authors: Benard Aswani, Ouna (Author) , Nyambega, Benson (Author) , Manful Gwira, Theresa (Author) , Helbig, Claudia (Author) , Maleš, Matilda (Author) , Fadda, Abeer (Author) , Clayton, Christine (Author)
Format: Article (Journal)
Language:English
Published: April 20, 2012
In: PLOS ONE
Year: 2012, Volume: 7, Issue: 4
ISSN:1932-6203
DOI:10.1371/journal.pone.0034256
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pone.0034256
Verlag, kostenfrei, Volltext: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034256
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Author Notes:Benard A. Ouna, Benson Nyambega, Theresa Manful, Claudia Helbig, Matilda Males, Abeer Fadda, Christine Clayton

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