Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase
Titin-like kinases are an important class of cytoskeletal kinases that intervene in the response of muscle to mechanical stimulation, being central to myofibril homeostasis and development. These kinases exist in autoinhibited states and, allegedly, become activated during muscle activity by the ela...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
August 21, 2012
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| In: |
Proceedings of the National Academy of Sciences of the United States of America
Year: 2012, Jahrgang: 109, Heft: 34, Pages: 13608-13613 |
| ISSN: | 1091-6490 |
| DOI: | 10.1073/pnas.1200697109 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1073/pnas.1200697109 Verlag, Volltext: http://www.pnas.org/content/109/34/13608 
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| Verfasserangaben: | Eleonore von Castelmur, Johan Strümpfer, Barbara Franke, Julijus Bogomolovas, Sonia Barbieri, Hiroshi Qadota, Petr V. Konarev, Dmitri I. Svergun, Siegfried Labeit, Guy M. Benian, Klaus Schulten, Olga Mayans |
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Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase
Bibliothek der Universität Konstanz 2012
Article (Journal)
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Online Resource