HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo
HIV-1 negative factor (Nef) elevates virus replication and contributes to immune evasion in vivo. As one of its established in vitro activities, Nef interferes with T-lymphocyte chemotaxis by reducing host cell actin dynamics. To explore Nef’s influence on in vivo recirculation of T lymphocytes, we...
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| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
October 23, 2012
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| In: |
Proceedings of the National Academy of Sciences of the United States of America
Year: 2012, Volume: 109, Issue: 45, Pages: 18541-18546 |
| ISSN: | 1091-6490 |
| DOI: | 10.1073/pnas.1204322109 |
| Online Access: | Verlag, LF, Volltext: http://dx.doi.org/10.1073/pnas.1204322109 Verlag, LF, Volltext: http://www.pnas.org/content/109/45/18541 |
| Author Notes: | Bettina Stolp, Andrea Imle, Fernanda Matos Coelho, Miroslav Hons, Roser Gorina, Ruth Lyck, Jens V. Stein, Oliver T. Fackler |
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