HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

HIV-1 negative factor (Nef) elevates virus replication and contributes to immune evasion in vivo. As one of its established in vitro activities, Nef interferes with T-lymphocyte chemotaxis by reducing host cell actin dynamics. To explore Nef’s influence on in vivo recirculation of T lymphocytes, we...

Full description

Saved in:
Bibliographic Details
Main Authors: Stolp-Rastätter, Bettina (Author) , Imle, Andrea (Author) , Fackler, Oliver Till (Author)
Format: Article (Journal)
Language:English
Published: October 23, 2012
In: Proceedings of the National Academy of Sciences of the United States of America
Year: 2012, Volume: 109, Issue: 45, Pages: 18541-18546
ISSN:1091-6490
DOI:10.1073/pnas.1204322109
Online Access:Verlag, LF, Volltext: http://dx.doi.org/10.1073/pnas.1204322109
Verlag, LF, Volltext: http://www.pnas.org/content/109/45/18541
Get full text
Author Notes:Bettina Stolp, Andrea Imle, Fernanda Matos Coelho, Miroslav Hons, Roser Gorina, Ruth Lyck, Jens V. Stein, Oliver T. Fackler
Search Result 1

The pathogenicity factor Nef in HIV-1 infection by Obermaier, Benedikt (Author)

2022

Get full text
Book/Monograph Thesis
Search Result 2

HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction by Schmidt, Sarah (Author) , Fritz, Joëlle (Author) , Bitzegeio, Julia (Author) , Fackler, Oliver Till (Author) , Keppler, Oliver Till (Author) ,


Get full text
Article (Journal) Online Resource