Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma: a SEER database analysis
Background: We the prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma (HCC) patients registered within the surveillance, epidemiology and end results (SEER) database.Methods: SEER database (2010-2013) has been queried through SEER*Stat program to determine the progno...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 Feb 2017
|
| In: |
Expert review of gastroenterology & hepatology
Year: 2017, Volume: 11, Issue: 7, Pages: 695-701 |
| ISSN: | 1747-4132 |
| DOI: | 10.1080/17474124.2017.1294485 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1080/17474124.2017.1294485 Verlag, Volltext: https://doi.org/10.1080/17474124.2017.1294485 
|
| Author Notes: | Hani Oweira, Arianeb Mehrabi |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1572490896 | ||
| 003 | DE-627 | ||
| 005 | 20230426124308.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180430s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/17474124.2017.1294485 |2 doi | |
| 035 | |a (DE-627)1572490896 | ||
| 035 | |a (DE-576)502490896 | ||
| 035 | |a (DE-599)BSZ502490896 | ||
| 035 | |a (OCoLC)1341007785 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Oweira, Hani |e VerfasserIn |0 (DE-588)1155884973 |0 (DE-627)1018363904 |0 (DE-576)501927395 |4 aut | |
| 245 | 1 | 0 | |a Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma |b a SEER database analysis |c Hani Oweira, Arianeb Mehrabi |
| 264 | 1 | |c 23 Feb 2017 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 30.04.2018 | ||
| 520 | |a Background: We the prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma (HCC) patients registered within the surveillance, epidemiology and end results (SEER) database.Methods: SEER database (2010-2013) has been queried through SEER*Stat program to determine the prognosis of advanced HCC patients according to the site of extra-hepatic disease. Survival analysis has been conducted through Kaplan Meier analysis.Results: A total of 4396 patients with stage IV HCC were identified in the period from 2010-2013 and they were included into this analysis. Patients with isolated regional lymph node involvement have better outcomes compared to patients with any other site of extra-hepatic disease (P < 0.0001 for both endpoints). Among patients with distant metastases, patients with bone metastases have better outcomes compared to patients with lung metastases (P < 0.0001 for both endpoints). Multivariate analysis revealed that younger age, normal alpha fetoprotein, single site of extra-hepatic disease, local treatment to the primary tumor and surgery to the metastatic disease were associated with better overall survival and liver cancer-specific survival.Conclusion: Within the limits of the current SEER analysis, HCC patients with isolated lung metastases seem to have worse outcomes compared to patients with isolated bone or regional nodal metastases. | ||
| 650 | 4 | |a bone metastases | |
| 650 | 4 | |a hepatocellular carcinoma | |
| 650 | 4 | |a Liver cancer | |
| 650 | 4 | |a lung metastases | |
| 650 | 4 | |a nodal metastases | |
| 700 | 1 | |a Mehrabi, Arianeb |d 1967- |e VerfasserIn |0 (DE-588)137664583 |0 (DE-627)594829763 |0 (DE-576)304831263 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Expert review of gastroenterology & hepatology |d Abingdon, Oxon : Taylor & Francis, 2007 |g 11(2017), 7, Seite 695-701 |h Online-Ressource |w (DE-627)594425875 |w (DE-600)2484623-5 |w (DE-576)398101035 |x 1747-4132 |7 nnas |a Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma a SEER database analysis |
| 773 | 1 | 8 | |g volume:11 |g year:2017 |g number:7 |g pages:695-701 |g extent:7 |a Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma a SEER database analysis |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/17474124.2017.1294485 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.1080/17474124.2017.1294485 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180430 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 137664583 |a Mehrabi, Arianeb |m 137664583:Mehrabi, Arianeb |d 910000 |d 910200 |e 910000PM137664583 |e 910200PM137664583 |k 0/910000/ |k 1/910000/910200/ |p 2 |y j | ||
| 998 | |g 1155884973 |a Oweira, Hani |m 1155884973:Oweira, Hani |p 1 |x j | ||
| 999 | |a KXP-PPN1572490896 |e 3007626668 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"disp":"Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma a SEER database analysisExpert review of gastroenterology & hepatology","recId":"594425875","part":{"volume":"11","pages":"695-701","text":"11(2017), 7, Seite 695-701","extent":"7","issue":"7","year":"2017"},"id":{"eki":["594425875"],"issn":["1747-4132"],"zdb":["2484623-5"]},"origin":[{"publisher":"Taylor & Francis ; Informa Healthcare","dateIssuedKey":"2007","dateIssuedDisp":"2007-","publisherPlace":"Abingdon, Oxon ; London"}],"pubHistory":["1.2007 -"],"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 01.09.15"],"title":[{"title":"Expert review of gastroenterology & hepatology","title_sort":"Expert review of gastroenterology & hepatology"}]}],"note":["Gesehen am 30.04.2018"],"name":{"displayForm":["Hani Oweira, Arianeb Mehrabi"]},"recId":"1572490896","id":{"eki":["1572490896"],"doi":["10.1080/17474124.2017.1294485"]},"origin":[{"dateIssuedDisp":"23 Feb 2017","dateIssuedKey":"2017"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"],"physDesc":[{"extent":"7 S."}],"person":[{"family":"Oweira","given":"Hani","role":"aut","display":"Oweira, Hani"},{"display":"Mehrabi, Arianeb","family":"Mehrabi","given":"Arianeb","role":"aut"}],"title":[{"title":"Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma","subtitle":"a SEER database analysis","title_sort":"Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma"}]} | ||
| SRT | |a OWEIRAHANIPROGNOSTIC2320 | ||