Dose-response of EBT3 radiochromic films to proton and carbon ion clinical beams
We investigated the dose-response of the external beam therapy 3 (EBT3) films for proton and carbon ion clinical beams, in comparison with conventional radiotherapy beams; we also measured the film response along the energy deposition-curve in water. We performed measurements at three hadrontherapy...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
[2017]
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| In: |
Physics in medicine and biology
Year: 2017, Jahrgang: 62, Heft: 2, Pages: 377-393 |
| ISSN: | 1361-6560 |
| DOI: | 10.1088/1361-6560/aa5078 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1088/1361-6560/aa5078 Verlag, Volltext: http://stacks.iop.org/0031-9155/62/i=2/a=377 
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| Verfasserangaben: | Roberta Castriconi, Mario Ciocca, Alfredo Mirandola, Carla Sini, Sara Broggi, Marco Schwarz, Francesco Fracchiolla, Mária Martišíková, Giulia Aricò, Giovanni Mettivier, Paolo Russo |
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| 520 | |a We investigated the dose-response of the external beam therapy 3 (EBT3) films for proton and carbon ion clinical beams, in comparison with conventional radiotherapy beams; we also measured the film response along the energy deposition-curve in water. We performed measurements at three hadrontherapy centres by delivering monoenergetic pencil beams (protons: 63-230 MeV; carbon ions: 115-400 MeV/u), at 0.4-20 Gy dose to water, in the plateau of the depth-dose curve. We also irradiated the films to clinical MV-photon and electron beams. We placed the EBT3 films in water along the whole depth-dose curve for 148.8 MeV protons and 398.9 MeV/u carbon ions, in comparison with measurements provided by a plane-parallel ionization chamber. For protons, the response of EBT3 in the plateau of the depth-dose curve is not different from that of photons, within experimental uncertainties. For carbon ions, we observed an energy dependent under-response of EBT3 film, from 16% to 29% with respect to photon beams. Moreover, we observed an under-response in the Bragg peak region of about 10% for 148.8 MeV protons and of about 42% for 398.9 MeV/u carbon ions. For proton and carbon ion clinical beams, an under-response occurs at the Bragg peak. For carbon ions, we also observed an under-response of the EBT3 in the plateau of the depth-dose curve. This effect is the highest at the lowest initial energy of the clinical beams, a phenomenon related to the corresponding higher LET in the film sensitive layer. This behavior should be properly modeled when using EBT3 films for accurate 3D dosimetry. | ||
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