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Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

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The first reconstitution of an unconventional secretory mechanism uncovered the molecular mechanism by which Fibroblast Growth Factor 2 is secreted from mammalian cells.

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Main Authors: Steringer, Julia P. (Author) , Müller, Hans-Michael (Author) , Unger, Sebastian (Author) , Nickel, Walter (Author)
Format: Article (Journal)
Language:English
Published: 19 July 2017
In: eLife
Year: 2017, Volume: 6, Pages: e28985
ISSN:2050-084X
DOI:10.7554/eLife.28985
Online Access:Verlag, LF, Volltext: http://dx.doi.org/10.7554/eLife.28985
Verlag, LF, Volltext: https://elifesciences.org/articles/28985
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Author Notes:Julia P Steringer, Sascha Lange, Sabína Čujová, Radek Šachl, Chetan Poojari, Fabio Lolicato, Oliver Beutel, Hans-Michael Müller, Sebastian Unger, Ünal Coskun, Alf Honigmann, Ilpo Vattulainen, Martin Hof, Christian Freund, Walter Nickel
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Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion by Ebert, Antje (Author) , Laußmann, Mareike (Author) , Wegehingel, Sabine (Author) , Kaderali, Lars (Author) , Erfle, Holger (Author) , Reichert, Jürgen (Author) , Lechner, Johannes (Author) , Beer, Hans-Dietmar (Author) , Pepperkok, Rainer (Author) , Nickel, Walter (Author) ,


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