Plasmodium falciparum variant erythrocyte surface antigens: a pilot study of antibody acquisition in recurrent natural infections
During intra-erythrocytic replication Plasmodium falciparum escapes the human host immune system by switching expression of variant surface antigens (VSA). Piecemeal acquisition of variant specific antibody responses to these antigens as a result of exposure to multiple re-infections has been propos...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
07 November 2017
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| In: |
Malaria journal
Year: 2017, Volume: 16 |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-017-2097-0 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1186/s12936-017-2097-0 Verlag, Volltext: https://doi.org/10.1186/s12936-017-2097-0 
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| Author Notes: | Elise Schieck, E. Jane Poole, Anja Rippert, Judy Peshu, Philip Sasi, Steffen Borrmann and Peter C. Bull |
| Summary: | During intra-erythrocytic replication Plasmodium falciparum escapes the human host immune system by switching expression of variant surface antigens (VSA). Piecemeal acquisition of variant specific antibody responses to these antigens as a result of exposure to multiple re-infections has been proposed to play a role in acquisition of naturally acquired immunity. |
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| Item Description: | Gesehen am 04.05.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-017-2097-0 |